Preoperativna volumetrijska analiza povezana je s većom učinkovitosti stereotaktičke evakuacije cističnih moždanih lezija i apscesa: retrospektivna usporedba s nevolumetrijskom evakuacijom u jednom centru

Scientific paper - Original scientific paper

• Title (english): Preoperative volumetry analysis is associated with higher rates of stereotactic evacuation of cystic brain lesions or abscess: A retrospective comparison with non-volumetry evacuation in a single center
• Author: Sergej Mihailovič Marasanov
• Author: Helena Ljulj
• Author: Hrvoje Barić
• Author's institution: University of Zagreb; School of Medicine; (Department of Pediatrics)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Pediatrics

Abstract (croatian)

Cilj. Preoperativna volumetrija koristi se za procjenu volumena tekućine u cističnim moždanim lezijama kod pacijenata kojima predstoji stereotaktička evakuacija ciste. Pretpostavili smo da preoperativna volumetrija može pomoći u optimizaciji opsega smanjenja volumena ciste pružanjem referentne vrijednosti volumena ciste. Cilj je ove studije procijeniti i izvijestiti o učinkovitosti evakuacije ciste s obzirom na (ne)izvedbu preoperativne volumetrijske analize. Ispitanici i metode. Pregledali smo arhivu Klinike da bismo identificirali bolesnike koji su bili podvrgnuti stereotaktičkoj aspiraciji cističnih moždanih lezija između siječnja 2013. i prosinca 2019. godine. Prikupljeni podatci uključivali su dob, spol i volumen ciste prije i nakon operacije svakog pacijenta. Podatci o pacijentima uspoređeni su između volumetrijske i nevolumetrijske skupine, također su uspoređeni preoperativni i postoperativni volumeni cista unutar grupa. Rezultati. Identificirali smo jedanaest pacijenata, osam s moždanim apscesom i troje s tumorskom cistom. Prosječna dob bila je 31 godina (raspon 6 – 64 godine), tri bolesnika bila su ženskog i osam muškog spola. Medijan preoperativnog volumena ciste bio je 21,0 cm3 (raspon 1,0 – 38,2 cm3), srednji postoperativni volumen 5,4 cm3 (0,8 – 16,1 cm3), medijan promjene volumena 9,7 cm3 (raspon 0,8 – 27,4 cm3). Kod pet pacijenata učinjena je preoperativna volumetrijska analiza (volumetrijska skupina) dok kod preostalih šest pacijenata nije (nevolumetrijska skupina). Nije bilo značajne razlike u dobi, spolu, preoperativnom volumenu, postoperativnom volumenu i promjeni volumena ciste između skupina. Srednji rezidualni cistični volumen u volumetrijskoj skupini bio je niži. Preoperativna nasuprot postoperativne razlike u volumenu ciste bila je značajna u volumetrijskoj skupini (10,8 cm3 do 2,7 cm3, p = 0,012) i nije bila značajna u nevolumetrijskoj skupini. Zaključak. Naši rezultati sugeriraju povezanost između volumetrijske analize i opsega evakuacije cističnih lezija mozga. Bez obzira na ograničenu veličinu uzorka, smatramo da su podatci indikativni i zahtijevaju daljnja istraživanja. Smatramo da bi volumetrijska procjena trebala biti standardna dijagnostička procedura kod svih pacijenata koji su podvrgnuti postupku stereotaktičke evakuacije moždanih cističnih lezija.

Abstract (english)

Aim. Preoperative volumetry is used to assess the volume of fluid in different brain cystic lesions in patients undergoing stereotactic cyst evacuation. We hypothesize that preoperative volumetry might aid in optimizing the extent of cyst volume reduction by providing a benchmark. We aimed to compare cyst evacuation efficacy with regard to (non) performance of preoperative volumetric analysis. Subjects and Methods. Clinical Hospital Center Zagreb digital archive was screened for patients who underwent stereotactic brain cyst aspiration between January 2013 and December 2019. Data were collected on patient age, sex, and pre- and postoperative cysts volumes. Patient data were compared between volumetry and non-volumetry group, also pre- vs. postoperative cyst volumes were compared intragroup. Results. We identified eleven patients, eight were operated for a brain abscess and three for a tumor cyst. Median age was 31 years (range 6–64), three were women and eight men. Median preoperative cyst volume was 21.0 cm3 (range 1.0–38.2 cm3), median postoperative volume 5.4 cm3 (0.8–16.1 cm3), median change in volume 9.7 cm3 (range 0.8–27.4 cm3). Five patients had a preprocedural volumetry (volumetry group) and six patients did not (non-volumetry group); there were no significant differences in age, sex, preoperative volume, postoperative volume, and volume change across groups. There was alower median residual cystic volume in the volumetry group. The pre- vs. postoperative difference in cyst volume was significant in the volumetry group (10.8 cm3 to 2.7 cm3, p = 0.012) and not significant in the non-volumetry group. Conclusion. Our results suggest an association between volumetric assessment and extent of brain cyst evacuation. Notwithstanding limitations due to sample size, we hold that the data are indicative and warrant further research. Volumetric analysis should be considered a standard diagnostic adjunct in all patients undergoing a brain cyst evacuation procedure.

• Keywords (croatian): moždani apsces – kirurgija, slikovna dijagnostika; moždani tumori – kirurgija, slikovna dijagnostika; ciste – kirurgija, slikovna dijagnostika; stereotaksijske tehnike; magnetska rezonancija; retrospektivna istraživanja
• Keywords (english): brain abscess – diagnostic imaging, surgery; brain neoplasms – diagnostic imaging, surgery; cysts – diagnostic imaging, surgery; stereotaxic techniques; magnetic resonance imaging; retrospective studies
• Language: croatian
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Liječnički vjesnik
• Numbering: vol. 145, no. 9-10, pp. 287-290
• p-ISSN: 0024-3477
• e-ISSN: 1849-2177
• DOI: https://doi.org/10.26800/LV-145-9-10-2
• URN:NBN: urn:nbn:hr:105:079876
• Publication: 2023
• Document URL: https://hrcak.srce.hr/309945
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-12-17 08:52:57