Dataset
Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown"
School of Medicine, 2024. urn:nbn:hr:105:917857
Šimunić, Iva

 Dataset
Dataset: d21_ipsc_1.tif, 96.08 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: d21_ipsc_2.tif, 96.08 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: d21_ipsc_3.tif, 104.08 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: d21_ipsc_4.tif, 104.08 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: d21_ipsc_5.tif, 120.09 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: t21_ipsc_1.tif, 136.09 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: t21_ipsc_2.tif, 136.09 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: t21_ipsc_3.tif, 192.1 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: t21_ipsc_4.tif, 192.1 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: t21_ipsc_5.tif, 152.08 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz organoida, iPSCs i NSCs (Croatian)

Dataset: d21_neurons_1.png, 1.26 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_2.png, 1.36 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_3.png, 1.34 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_4.png, 1.21 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_5.png, 1.09 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_6.png, 1.35 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_7.png, 1.29 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_8.png, 1.42 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_9.png, 1.14 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_10.png, 1.32 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_11.png, 1.33 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_12.png, 1.33 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_13.png, 1.28 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_14.png, 1.24 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: d21_neurons_15.png, 1.32 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_1.png, 1.35 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_2.png, 1.24 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_3.png, 1.32 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_4.png, 1.27 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_5.png, 1.39 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_6.png, 1.52 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_7.png, 1.36 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_8.png, 1.37 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_9.png, 1.36 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_10.png, 1.25 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_11.png, 1.56 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_12.png, 1.41 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_13.png, 1.42 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_14.png, 1.6 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: t21_neurons_15.png, 1.54 MB
Access Condition: Access restricted to institution's students and staff
Description:
Imunohistokemijski prikaz neurona (Croatian)

Dataset: upute_-_instructions.pdf, 561.79 KB
Access Condition: Access restricted to institution's students and staff
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Cite this document

Šimunić, I. (2024). Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown" [Data set]. https://urn.nsk.hr/urn:nbn:hr:105:917857.

Šimunić, Iva. Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown". Medicinski fakultet, 2024. 01 Apr 2025. https://urn.nsk.hr/urn:nbn:hr:105:917857.

Šimunić, Iva. 2024. Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown". Medicinski fakultet. https://urn.nsk.hr/urn:nbn:hr:105:917857.

Šimunić, I. 2024. Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown". Medicinski fakultet. [Online]. [Accessed 01 April 2025]. Available from: https://urn.nsk.hr/urn:nbn:hr:105:917857.

Šimunić I. Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown". [Internet]. Medicinski fakultet: Zagreb, HR; 2024, [cited 2025 April 01] Available from: https://urn.nsk.hr/urn:nbn:hr:105:917857.

I. Šimunić, Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown", Medicinski fakultet, 2024. Accessed on: Apr 01, 2025. Available: https://urn.nsk.hr/urn:nbn:hr:105:917857.

Title (croatian)Skup podataka projekta "Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga - DevDown"
AuthorIva Šimunić
Sveučilište u Zagrebu, Medicinski fakultet
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Neuroscience
Abstract (croatian)
Jedan od ciljeva projekta je razviti repozitorij slika cerebralnih organoida dobivenih iz jedinstvenih staničnih linija koje se razlikuju po prisutnosti dodatnog kromosoma 21. Organoidi su uzgojeni kako bi se proučili ključni procesi koji se odvijaju tijekom razvoja in vitro modela ljudskog moždanog korteksa. Fokus je na razumijevanju utjecaja dodatnog kromosoma na razvoj moždanih struktura, što može pružiti uvid u razvojne mehanizme povezanih poremećaja. Repozitorij slika služi kao vrijedan resurs za analizu i usporedbu morfologije i funkcionalnih svojstava ovih modela, omogućujući napredak u istraživanjima neuroznanosti i genetskih bolesti.
Methods (croatian)Inducirane pluripotentne matične stanice (iPSC), živčane matične stanice (NSC) i cerebralni organoidi su uzgojeni i umnoženi prema standardiziranim, objavljenim protokolima, osiguravajući dosljednost i reproducibilnost. Nakon fiksacije, organoidi su prošli postupak krioprotekcije, uklopljeni su i narezani na kriostatu u tanke rezove od 20 µm, koji su naneseni na predmetna stakla za imunohistokemijske analize. Rezovi su zatim obojeni imunohistokemijskim tehnikama prema dostupnim protokolima. Konačno, imunohistokemijski obrađeni uzorci snimljeni su konfokalnom mikroskopijom, čime je omogućena detaljna vizualizacija i analiza staničnih i tkivnih struktura.
Keywords (croatian)
Languagecroatian
URN:NBNurn:nbn:hr:105:917857
Publication2024-12-18
Created2024
GeolocationZagreb, Croatia
ProjectNumber: IP-2022-10-4656
Title (croatian): Otkrivanje neurorazvojne osnove Downovog sindroma pomoću jedinstvenih organoida ljudskog mozga
Title (english): Revealing the Neurodevelopmental Basis of Down Syndrome on a Unique Human Brain Organoid Model
Acronym: DevDown
Leader: Dinko Mitrečić
Jurisdiction: Croatia
Funding stream: Research Projects
PublisherMedicinski fakultet
School of Medicine
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2024-12-18 07:48:45