prikaz prve stranice dokumenta JC Virus in Kidney Transplant Population: Are We Cautious Enough?
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Scientific paper - Review paper
JC Virus in Kidney Transplant Population: Are We Cautious Enough?
Journal of Clinical Medicine, 13 (2024), 8; 2217. https://doi.org/10.3390/jcm13082217
Pjanic, Mirha; Aleckovic-Halilovic, Mirna; Bašić-Jukić, Nikolina

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Pjanic, M., Aleckovic Halilovic, M. & Bašić Jukić, N. (2024). JC Virus in Kidney Transplant Population: Are We Cautious Enough?. Journal of Clinical Medicine, 13. (8). doi: 10.3390/jcm13082217

Pjanic, Mirha, et al. "JC Virus in Kidney Transplant Population: Are We Cautious Enough?." Journal of Clinical Medicine, vol. 13, no. 8, 2024. https://doi.org/10.3390/jcm13082217

Pjanic, Mirha, Mirna Aleckovic Halilovic and Nikolina Bašić Jukić. "JC Virus in Kidney Transplant Population: Are We Cautious Enough?." Journal of Clinical Medicine 13, no. 8 (2024). https://doi.org/10.3390/jcm13082217

Pjanic, M., Aleckovic Halilovic, M. and Bašić Jukić, N. (2024) 'JC Virus in Kidney Transplant Population: Are We Cautious Enough?', Journal of Clinical Medicine, 13(8). doi: 10.3390/jcm13082217

Pjanic M, Aleckovic Halilovic M, Bašić Jukić N. JC Virus in Kidney Transplant Population: Are We Cautious Enough?. Journal of Clinical Medicine [Internet]. 2024 April 11 [cited 2025 March 17];13(8). doi: 10.3390/jcm13082217

M. Pjanic, M. Aleckovic Halilovic and N. Bašić Jukić, "JC Virus in Kidney Transplant Population: Are We Cautious Enough?", Journal of Clinical Medicine, vol. 13, no. 8, April 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:907160. [Accessed: 17 March 2025]

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Metadata
Title (english)JC Virus in Kidney Transplant Population: Are We Cautious Enough?
AuthorMirha Pjanic
AuthorMirna Aleckovic-Halilovic
AuthorNikolina Bašić-Jukić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The John Cunningham virus (JCV) is a polyomavirus that usually infects people at a young age and does not cause any symptoms in immunocompetent individuals. However, in immunocompromised individuals, such as kidney transplant recipients, JCV can cause severe and potentially fatal disease. Unfortunately, JCV has not been researched as extensively as the BK virus and is not mentioned in relevant kidney transplant guidelines. This lack of attention to JCV can lead to less consideration in kidney transplant patients’ care. Surveillance using locally available diagnostic methods is of the utmost importance. The presence of JCV can be diagnosed with urine decoy cells, viruria, or viremia verified by the PCR method. A low threshold for considering JCV as a possible cause of any neurological or renal dysfunction in kidney transplant recipients must be maintained. In such cases, kidney and brain biopsy are indicated. Maintaining the appropriate immunosuppression while avoiding over-immunosuppression to prevent JCV disease is crucial, and the approach should be individual, according to overall immunological risk. We hypothesize that the presence of the JCV can indicate overt immunosuppression and identify kidney transplant recipients more prone to opportunistic infections and diseases, including some malignancies. To explore that, future observational studies are needed.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Clinical Medicine
Numberingvol. 13, no. 8, 2217
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm13082217
URN:NBNurn:nbn:hr:105:907160
Publication2024-04-11
Document URLhttps://www.mdpi.com/2077-0383/13/8/2217
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2025-03-03 09:23:27