Neinvazivne metode u dijagnostici ishemijske bolesti srca

master's thesis

• Title (english): Non-invasive methods in the diagnosis of ischemic heart disease
• Author: Kristina Marelja
• Mentor: Mislav Puljević (mentor)
• Committee member: Martina Lovrić-Benčić (predsjednik povjerenstva)
• Committee member: Jasenka Markeljević (član povjerenstva)
• Committee member: Mislav Puljević (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2016-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Ishemijska bolest srca je danas kako su svijetu, tako i u Hrvatskoj, značajan javnozdravstveni problem. Posljedica je poremećene cirkulacije kroz aterosklerotski promijenjene koronarne krvne žile. Kao skup kliničkih sindroma, ishemijska bolest srca uključuje stabilnu anginu pektoris kao kronično stanje i akutni koronarni sindrom kao akutnu manifestaciju.
Na ozbiljnost ishemijske bolesti srca ukazuju podatci Svjetske zdravstvene organizacije prema kojima više od 7 milijuna ljudi umire svake godine od posljedica ove bolesti, a na razini naše zemlje svaki drugi stanovnik umire od infarkta miokarda, najtežeg kliničkog oblika ishemijske bolesti srca. Iz tog je razloga veliki dijagnostički izazov otkriti i dijagnosticirati ishemiju miokarda prije nego se razvije nekroza kao ireverzibilna promjena, a na osnovu toga odlučiti o daljnjem terapijskom planu. Brojne su dijagnostičke metode na raspolaganju liječnicima u dijagnostičkom postupku, neinvazivne i invazivne. Među neinvazivne spadaju elektrokardiografija (EKG), ehokardiografija, magnetna rezonanca srca, perfuzijska scintigrafija miokarda, te CT angiografija. Svaka od njih se može izvoditi u mirovanju i pod opterećenjem, fizikalnim ili farmakološkim. Nijedna metoda nije u potpunosti učinkovita, ali svaka od njih ima svoje važno mjesto u dijagnostičkom postupku.

Abstract (english)

Ischemic heart disease is an important public health problem today in whole world. It is a result of inadequate blood circulation trough coronary arteries changed by atherosclerosis process.
It is a group of clinical syndromes that include stabile angina pectoris and acute coronary syndrome. Due to the information of World Health Organisation more than 7 million people die every year of consequences of this disease. In Croatia almost every second person dies of acute myocardial infarction, the most difficult consequence of ischemic heart disease. Therefore, there is reasonable diagnostic challenge to detect and diagnose ischemia of myocardium before the development of irreversible necrosis and on the basis of that decide about other diagnostic and therapeutic methods. There is great number of diagnostic methods available to physicians. There are non-invasive and invasive diagnostic methods. Non-invasive methods are electrocardiography, echocardiography, magnetic resonance, perfusion scintigraphy of myocardium and CT angiography. Each of these methods can be performed in a rest and during the stress, exercise or stress caused by medicaments.
None of these methods is completely effective, but each of them has an important role in the diagnostic process of ischemic heart disease.

• Keywords: ishemijska bolest srca; ateroskleroza; dijagnostičke metode; neinvazivne
• Keywords (english): ischemic heart disease; diagnostic methods; non-invasive methods
• Language: croatian
• URN:NBN: urn:nbn:hr:105:832411
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-07-13 09:45:36