Non melanoma skin cancer

master's thesis

• Author: Velimir Vuk
• Mentor: Romana Čeović (mentor)
• Committee member: Zrinka Bukvić Mokos (predsjednik povjerenstva)
• Committee member: Krešimir Kostović (član povjerenstva)
• Committee member: Romana Čeović (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2016-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Dermatovenerology

Abstract

Non melanoma skin cancer is the most frequently occurring human malignancy. It is encountered all over the world, particularly in areas with high exposure to its primary risk factor, sunlight. The pathogenesis involves signature UV mutations in genes coding for tumor suppression and growth signalling. Early identification of suspicious lesions is significant because the various therapies available are most effective for localized disease. The elucidation of the MAPK and PI3K growth pathways in cutaneous squamous cell carcinoma and the Sonic Hedgehog signalling pathway in basal cell carcinoma have led to the development of novel treatments for metastatic disease.

• Keywords: basal cell carcinoma; non melanoma skin cancer; cutaneous squamous cell carcinoma
• Language: english
• URN:NBN: urn:nbn:hr:105:965657
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-08-31 09:31:10