Etiologija i liječenje sekundarne hipertenzije

master's thesis

• Title (english): Etiology and management of secondary hypertension
• Author: Tomislav Čikara
• Mentor: Diana Delić-Brkljačić (mentor)
• Committee member: Matias Trbušić (predsjednik povjerenstva)
• Committee member: Jasenka Markeljević (član povjerenstva)
• Committee member: Diana Delić-Brkljačić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2017-07-14, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Arterijska hipertenzija je stanje trajno povišenih vrijednosti krvnog tlaka. Definira se vrijednostima sistoličkog tlaka 140 mmHg i/ili dijastoličkog tlaka 90 mmHg. Arterijska hipertenzija može biti primarna i sekundarna. Sekundarna hipertenzija je arterijska hipertenzija poznatog uzroka. Obuhvaća 5-10% bolesnika s arterijskom hipertenzijom. Hipertenzija rezistentna na terapiju sa specifičnim kliničkim znakovima i simptomima može ukazivati na sekundarnu hipertenziju. Etiologija sekundarne hipertenzije se može podijeliti na: poremećaje bubrega, endokrine poremećaje, supstance koje mogu uzrokovati povišenje arterijskog tlaka, trudnoću kao uzrok povišenja krvnog tlaka, opstruktivnu apneju u snu, koarktaciju aorte te ostale uzroke sekundarne hipertenzije. Postavljanje dijagnoze i otkrivanje uzroka povišenog arterijskog tlaka izrazito je bitno jer se često radi o potencijalno izlječivom i reverzibilnom stanju. Sekundarna hipertenzija liječi se uklanjanjem uzroka koji su doveli do njenog nastanka. Osim farmakološke terapije sekundarna hipertenzija često se liječi metodama intervencijske radiologije i kirurškim zahvatima.

Abstract (english)

Arterial hypertension is a condition in which the blood pressure is persistently elevated. It is defined as systolic blood pressure 140 mmHg and/or diastolic blood pressure 90 mmHg. Arterial hypertension can be primary or secondary. Secondary hypertension is arterial hypertension due to an identifiable cause. It affects 5-10% of patients with hypertension. Hypertension resistant to medication with specific clinical signs and symptoms may suggest secondary hypertension. Etiology of secondary hypertension can be classified as: renal disorders, endocrine disorders, drugs-induced hypertension, pregnancy-induced hypertension, obstructive sleep apnea, coarctation of the aorta and miscellaneous. The diagnosis of secondary hypertension and finding the cause of hypertension is important to make, as curative treatment may be available. The secondary hypertension is managed by treating the cause of high blood pressure. Beside pharmacologic treatment the management of secondary hypertension is often surgery.

• Keywords: arterijska hipertenzija; sekundarna hipertenzija; stenoza renalnih arterija; primarni aldosteronizam; opstruktivna apneja u snu; koarktacija aorte
• Keywords (english): arterial hypertension; secondary hypertension; renal artery stenosis; primary aldosteronism; obstructive sleep apnea; coarctation of the aorta
• Language: croatian
• URN:NBN: urn:nbn:hr:105:016717
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-16 09:44:48