Transplantacija bubrega u bolesnika s psihomotornom retardacijom

master's thesis

• Title (english): Kidney transplantation in patients with psychomotor retardation
• Author: Ivan Remaj
• Mentor: Nikolina Bašić Jukić (mentor)
• Committee member: Željko Kaštelan (predsjednik povjerenstva)
• Committee member: Martina Lovrić Benčić (član povjerenstva)
• Committee member: Nikolina Bašić Jukić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2017-07-14, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Kronična bubrežna bolest je progresivan gubitak bubrežne funkcije tijekom nekoliko mjeseci ili godina. U završnim fazama bolesti, bolesnicima je potrebna terapija zamjene bubrežne funkcije u obliku dijalize ili transplantacije bubrega. Kvaliteta života i preživljenje bolesnika na dijalizi je značajnije manja nego kod transplantacije bubrega. Bolesnici s psihomotornom retardacijom se često smatraju lošim kandidatima za transplantaciju bubrega jer se vjeruje da imaju smanjen životni vijek, slabu suradljivost vezanu uz posttransplantacijsku terapiju i nedostatak kognitivne sposobnosti da bi shvatili operaciju. Ovi bolesnici uglavnom spadaju ili u kategoriju relativnih ili apsolutnih komplikacija s obzirom na razinu intelektualnih sposobnosti, obično mjereno IQ-om. Glavni cilj ovog rada je pokazati da se ova kontraindikacija može nadvladati pomoću potpore legalnih skrbnika koji kompenziraju bolesnikove nedostatke. Ova studija uključuje 7 bolesnika, 4 žene i 3 muškarca. Retrospektivno smo analizirali stope preživljenja, razinu kreatinina, stope komplikacija i tjelesnu težinu.

Abstract (english)

Chronic kidney disease is progressive loss of kidney function over the period of months or years. In the final stages of the disease, patients require kidney replacement therapy in the form of dialysis or kidney transplant. The quality of life and survival rates in chronic kidney disease patients on dialysis is significantly different from patients who had undergone a kidney transplant. Patients with psychomotor retardation are often considered subpar candidates for kidney transplantation due to belief of their reduced life expectancy, inability to comply with postoperative therapy and lack of cognitive understanding of the procedure itself. These patients are considered to fall either in a relative or absolute contraindication category depending on the level of their intellectual disability usually measured by their IQ. Main goal of this paper is to show how this contraindication can be overcome by the support of legal guardians who can compensate for the patients limitations. This study includes 7 patients, 4 females and 3 males. We retrospectively analyse survival rates, serum creatinine levels, complication rates and body weight.

• Keywords: kronična bubrežna bolest; dijaliza; transplantacija; psihomotorna retardacija
• Keywords (english): chronic kidney disease; dialysis; transplantation; psychomotor retardation
• Language: croatian
• URN:NBN: urn:nbn:hr:105:059857
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-26 10:46:44