Hipertenzivni poremećaji u trudnoći

master's thesis

• Title (english): Hypertensive disorders in pregnancy
• Author: Romina Kalesić Čulina
• Mentor: Vesna Elveđi Gašparović (mentor)
• Committee member: Tomislav Čanić (predsjednik povjerenstva)
• Committee member: Dinka Pavičić-Baldani (član povjerenstva)
• Committee member: Vesna Elveđi Gašparović (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Gynecology and Obstetrics); Zagreb
• Defense date and country: 2014-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics

Abstract

Većina žena očekuje da će trudnoća i porođaj za njih biti isključivo sretno razdoblje. No ponekad se događaju ozbiljne komplikacije. Najučestaliji medicinski problem koji se javlja tijekom trudnoće i komplicira 2-3% svih trudnoća jest hipertenzija. Radna skupina za visoki tlak u trudnoći Američkog edukacijskog programa za visoki tlak klasificira hipertenzivne poremećaje u trudnoći u 4 kategorije: kronična hipertenzija, preeklampsija/eklampsija, preeklampsija superponirana na kroničnu hipertenziju i gestacijska hipertenzija. (National High Blood Pressure Education Program Working Group 2000).
Važnost hipertenzivnih poremećaja u trudnoći leži u njihovom utjecaju na različite organske sustave od kojih su poremećaji nekih od njih i životno-ugrožavajući. Ovi se poremećaji povezuju s povišenim rizikom od nepovoljnih ishoda kako kod majke tako i kod fetusa.
Maternalne komplikacije uključuju eklamptične napadaje, intracerebralno krvarenje, plućni edem (zbog povećane kapilarne propusnosti, disfunkcije miokarda, prekomjernog intravenskog davanja tekućine), akutno zatajenje bubrega (zbog vazospazma, akutne tubularne nekroze ili renalne kortikalne nekroze), proteinuriju, HELLP sindrom...
Hipertenzija u trudnoći nepovoljno utječe i na fetus. Najčešće fetalne komplikacije uključuju abrupciju placente, intrauterini zastoj u rastu, prijevremeni porod te intrauterinu smrt fetusa.

Abstract (english)

Most women enter pregnancy with the expectation that their pregnancy and delivery will involve nothing but happiness. But sometimes severe complications can occur. The most common medical problem encountered during pregnancy, complicating 2-3% of pregnancies, is hypertension. Hypertensive disorders during pregnancy are classified into 4 categories, as recommended by the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy: chronic hypertension, preeclampsia/eclampsia, preeclampsia superimposed on chronic hypertension and gestational hypertension.
The importance of hypertensive disorders of pregnancy lies in their impact on different organ systems some of which can become life-threatening. These disorders are associated with increased risk of both adverse maternal and fetal outcomes. Maternal complications include eclamptic seizures, intracerebral haemorrhage, pulmonary edema (due to capillary leak, myocardial dysfunction, excess IV fluid administration), acute renal failure (due to vasospasm, acute tubular necrosis or renal cortical necrosis), proteinuria, HELLP syndrome...
As previously mentioned hypertension during pregnancy affects not only the mother but also a fetus. Most common fetal complications include abruptio placentae, intrauterine growth restriction, premature delivery and intrauterine fetal death.

• Keywords: hipertenzija; trudnoća; preeklampsija; eklampsija; komplikacije
• Keywords (english): hypertension; pregnancy; preeclampsia; eclampsia; complications
• Language: croatian
• URN:NBN: urn:nbn:hr:105:526625
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-10-20 16:17:56