Karakteristike Toxoplasma gondii infekcije u trudnica i novorođenčadi

master's thesis

• Title (english): Characteristics of Toxoplasma gondii infection in pregnancy and newborns
• Author: Ana-Marija Ljubenković
• Mentor: Mario Sviben (mentor)
• Committee member: Tatjana Vilibić Čavlek (predsjednik povjerenstva)
• Committee member: Goran Tešović (član povjerenstva)
• Committee member: Mario Sviben (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Medical Microbiology and Parasitology); Zagreb
• Defense date and country: 2018-07-13, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Medical Microbiology

Abstract

Toksoplazmoza se smatra jednom od najraširenijih infekcija na svijetu. Do kongenitalne toksoplazmoze dolazi u slučaju akutne infekcije majke tijekom trudnoće, a njezine posljedice mogu biti oštećenja središnjeg živčanog sustava, oka i srca te razne anomalije. Serološko testiranje treba biti dostupno svima pod rizikom za akutnu Toxoplasma gondii infekciju tijekom trudnoće, imunokompromitiranim pacijentima, HIV-pozitivnim osobama i pacijentima na dugotrajnoj kortikosteroidnoj terapiji. Pirimetamin sa sulfadiazinom te folnom kiselinom preporučuje se u slučaju sumnje na fetalnu infekciju ili potvrđene infekcije. Edukacijske mjere su važne za prevenciju akutne toksoplazmoze u trudnica, a uključuju izbjegavanje kontakta s mačjim fecesom, nekonzumiranje sirovog ili nedovoljno termički obrađenog mesa i temeljito pranje svježeg voća i povrća prije konzumacije.

Abstract (english)

Toxoplasmosis is considered to be one of the most common infections in the world. Congenital toxoplasmosis occurs if the mother acquires an acute infection during pregnancy, and it can cause neurological disorder, ocular and heart problems and different types of anomalies. Serologic screening must to be proposed to those thought to be at risk for primary Toxoplasma gondii infection during pregnancy as well as to those who are immunosuppressed, HIV-positive, or on long-term corticosteroid therapy. Pyrimethamine with sulfadiazine and folinic acid is recommended when fetal infection has been suspected or infection has been confirmed. Prenatal care must include education about prevention of toxoplasmosis, which includes avoiding cat feces as well as avoiding raw or undercooked meat and washing raw fruit and vegetables well before eating.

• Keywords: kongenitalna toksoplazmoza; trudnoća; prevencija
• Keywords (english): congenital toxoplasmosis; pregnancy; prevention
• Language: croatian
• URN:NBN: urn:nbn:hr:105:960428
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-01-04 11:08:20