Characteristics of patients with chronic rhinosinusitis who underwent endoscopic sinus surgery

master's thesis

• Title (croatian): Značajke bolesnika s kroničnim rinosinusitisom liječenih endoskopskom sinusnom kirurgijom
• Author: Jeffry Mattar
• Mentor: Tomislav Baudoin (mentor)
• Committee member: Livije Kalogjera (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Tomislav Baudoin (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery); Zagreb
• Defense date and country: 2018-07-13, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract

This study assessed the characteristics of patients with CRS, with or without nasal polyps, who underwent ESS as part of their treatment for sinonasal disease at the Department of ORL HNS, Sisters of Charity University Hospital in Zagreb and compared the results to other studies done on CRS patients. Patients who were operated during a year period of 2016 were audited. The data collected included demographic features of patients, risk factors exposure, diagnosis, and type of endoscopic surgical procedures which were performed to treat the sinonasal disease. The purpose of the study was to understand the characteristics of patients who need ESS as part of their treatment course. In total, 189 patients were included in the study. Of which, 67% of the
participants (85 males and 46 females) are diagnosed with CRSwNP and 31% (30 males and 28 females) are diagnosed with CRSsNP, 2% are diagnosed with CRS with tumor. In this study 13 patients were in the age group of <18 years (6.8%), followed by 28 in the age group of 19-30 (14.8%), 54 patients were in the age group of 31-45 (28.5%), 57 patients were in the age group of 46-60 (30%), and 37 patients were above 60 years (19.5%). The mean age for patients with CRSwNP was 49.2 and for the patients with CRSsNP was 38.7. The results showed that male gender was more associated with nasal polyps and that the frequencies of allergy, asthma, and aspirin sensitivity were significantly higher than for patients diagnosed with CRSsNP. Patients with CRSwNP tend to undergo more than one endoscopic procedure compared to patient without polyps. Septal deviation was more prevalent in the CRSsNP group (55%) when compared to CRSwNP (25.2%). The majority of the patients who underwent surgery had multiple sinuses involved (40%). Single-sinus operations were more common among ethmoid (17%) and maxillary (13%) sinuses.

Abstract (croatian)

U ovom istraživanju proučavaju se značajke pacijenata s dijagnozom kroničnog rinosinusitisa, od kojih neki imaju pridruženu nosnu polipozu, a liječeni su endoskopskom sinusnom kirurgijom na Klinici za otorinolaringologiju i kirurgiju glave i vrata u KBC Sestre milosrdnice u Zagrebu tijekom 2016. godine. Prikupljeni podaci uključuju demografske karakterisitke pacijenata, faktore rizika, dijagozu i vrstu endoskopske operacije koja je izvedena. Svrha ovog istraživanja je istražiti značajke pacijenata kojima je potrebna endoskopska operacija sinusa kao dio liječenja. U istraživanje je uključeno ukupno 189 pacijenata, od kojih je 67% (85 muškaraca i 46 žena) imalo dijagnozu kroničnog rinosinusitisa s nosnim polipima, a 31% (30 muškaraca i 28 žena) imalo dijagnozu kroničnog rinusinusitisa bez nosnih polipa. Samo 2% pacijenata imalo je pridruženi tumor uz dijagnozu kroničnog rinosinusitisa. U ovom istraživanju 13 pacijenata nalazi su u dobnoj skupini mlađoj od 18 (6.8%), 28 pacijenata je u grupi od 19-30 (14.8%), 54 pacijenata u grupi od 31-45 (28.5%) godina, 57 njih nalazi se u grupi od 46-60 (30%) godina i 37 pacijenata je starije od 60 godina (19,5%). Prosječna dob pacijenata s nosnim polipima je 49.2, a onih bez polipa je 38.7. Rezultati su pokazali da je prisutnost polipa veća u muškog spola te da je učestalost polipa veća u pacijenata koji imaju astmu, alergije ili su preosjetljvi na aspirin. Pacijenti s polipima su češće operirani više puta u odnosu na pacijenete s kroničnim rinosinusitisom bez polipa. Prevalencija septalne devijacije je veća u pacijenata bez polipa (55%) u odnosu na pacijente s polipima (25.2%). Većina pacijenata koji su endoskopski operirani imali su bolest prisutnu u više sinusa, s time da je najčešće upala bila prisutna u etmoidnim (17%) i maksilarnim (13%) sinusima.

• Keywords: chronic rhinosinusitis; chronic rhinosinusitis with nasal polyps; nasal polyps; endoscopic sinus surgery
• Keywords (english): kronični rinosinusitis; kronični rinosinusitis s nosnim polipima; nosni polipi; endoskopska kirurgija sinusa
• Language: english
• URN:NBN: urn:nbn:hr:105:430582
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-04-18 09:35:42