Moderno liječenje ranopojavnih skolioza

master's thesis

• Title (english): Modern treatment of early-onset scoliosis
• Author: Dora Martinčević
• Mentor: Tomislav Đapić (mentor)
• Committee member: Domagoj Delimar (predsjednik povjerenstva)
• Committee member: Ivan Bojanić (član povjerenstva)
• Committee member: Tomislav Đapić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Orthopedics); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Orthopedics

Abstract

Ovaj diplomski rad prvenstveno govori o skoliozi, njenoj etiologiji, kategorizaciji te utjecaju na rast i razvoj ostalih organa uz poseban osvrt na dosadašnje liječenje te današnje napretke u liječenju i moguće buduće smjernice.
Skolioza je stanje u kojem dolazi do odstupanja od normalne zakrivljenosti kralježnice, pri čemu nastaje pojačana postranična zakrivljenost uz posljedičnu rotaciju kralježaka unutar zavoja. Ranopojavne skolioze su skolioze koje se javljaju prije navršene 10. godine života, a mogu se javiti u sklopu kongenitalnih anomalija kralježnice, neuromuskularnih bolesti, pojedinih sindroma ili kao idiopatske. S obzirom na široku i raznovrsnu etiologiju, skolioze obuhvaćaju veoma inhomogenu skupinu bolesnika, a liječenje je često veoma kompleksno te često zahtijeva brojne operacije. S obzirom na ranu dob u kojoj se javljaju, ranopojavne skolioze predstavljaju značajan rizik za bolesnike zbog kompromitacije plućne funkcije. Progresivna deformacija kralježnice u ranoj životnoj dobi dovodi do izostanka normalnog razvoja pluća i prsnog koša.
Liječenje skolioze može biti konzervativno ili kirurško. Odabir metode liječenja ovisi o tipu skolioze, dobi bolesnika, veličini zavoja te riziku progresije i podležećim komorbiditetima, a načelno se započinje konzervativnim liječenjem čiji je cilj zaustaviti progresiju ili odgoditi operaciju do dobi postizanja adekvatnog plućnog kapaciteta i kralježničkoga rasta. U slučaju neuspjeha konzervativnih metoda ili velike progresije krivulje, kirurško liječenje postaje metoda izbora.

Abstract (english)

This graduate thesis primarily focuses on scoliosis etiology, categorization and its impact on the growth and development of other organs, with a special review of the current treatment and possible future guidelines.
Scoliosis is a spinal deformity consisting of lateral curvature and rotation of the vertebrae. Early-onset scoliosis includes those presenting before the age of 10 years, and may either be associated with congenital abnormalities of the spine, neuromuscular diseases and some syndromes or it can be idiopathic. Given the wide and varied etiology, scoliosis covers a very inhomogeneous group of patients, and its’ treatment is often very complex and requires multiple surgical corrections. With regard to the early age of onset, scoliosis carries a significant risk of lung function failure due to the progressive spinal deformation in the critical time of pulmonary capacity development. Treatment options for scoliosis can be classified as either conservative or surgical. The choice of treatment method depends on the type of scoliosis, patient’s age, magnitude of the curve, risk of further progression and the underlying comorbidities. Usually, the treatment begins with a conservative method whose aim is to halt the progression of the curve or to delay a surgical treatment until the adequate lung capacity and spinal growth are reached. In case of conservative method failure or a large curve progression, surgical treatment becomes the method of choice.

• Keywords: kralježnica; ranopojavna skolioza; prsni koš; pluća; liječenje
• Keywords (english): spine; early-onset scoliosis; pulmonary capacity; lung function; treatment
• Language: croatian
• URN:NBN: urn:nbn:hr:105:987677
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-10-21 11:56:21