Primarne progresivne afazije

master's thesis

• Title (english): Primary progressive aphasia
• Author: Matea Janković
• Mentor: Marina Boban (mentor)
• Committee member: Srđana Telarović (predsjednik povjerenstva)
• Committee member: Mario Habek (član povjerenstva)
• Committee member: Marina Boban (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Neurology); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Neurology

Abstract

Primarne progresivne afazije (PPA) su još nedovoljno istražena skupina primarnih neurodegenerativnih demencija koje su posljednjih nekoliko desetljeća postale područje interesa znanstvenika. PPA se dijeli u tri varijante: nefluentnu, semantičku i logopeničnu varijantu. Svima je zajedničko predominantno, rano zahvaćanje govora koje ometa svakodnevno funkcioniranje oboljelog. Ipak svaka varijanta ima karakterističnu kliničku sliku, neuroradiološki te histopatološki nalaz. Specifična farmakološka terapija nije dostupna; stoga se liječenje sastoji od suportivne farmakološke i nefarmakološke terapije. Naglasak je stavljen na nefarmakološku terapiju koja obuhvaća rehabilitaciju govora, edukaciju oboljelih i okoline, pojačanu fizičku aktivnost, procjenu sigurnosti okoline i sposobnosti oboljelih za upravljanje motornim vozilom.

Abstract (english)

Primary Progressive Aphasia (PPA) is still not sufficiently known group of primary neurodegenerative dementia that has become an area of interest of scientists over the last two decades. PPA is divided into three variants: nonfluent, semantic and logopenic variant. Whole group is characterized by prominent early speech problems; however, each variant has a characteristic clinical picture, neuroradiological and histopathological findings. Specific therapy is not yet available; therefore, current treatment consists of supportive pharmacological and nonpharmacological therapy. An emphasis is on non-pharmacological therapy, which includes rehabilitation of speech, education of the patients and their families, physical activity, assessment of the environmental safety for the patient and ability to drive a car.

• Keywords: primarne progresivne afazije; PPA; primarne neurodegenerativne demencije; nefarmakološka terapija
• Keywords (english): primary progressive aphasia; PPA; primary neurodegenerative dementia; non-pharmacological therapy
• Language: croatian
• URN:NBN: urn:nbn:hr:105:669482
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Public note: Pohranitelj objekta unio ključne riječi.
• Created on: 2020-06-10 09:07:10