Management of acute gastrointestinal bleeding in the emergency medicine setting

master's thesis

• Title (croatian): Obrada i liječenje akutnog gastrointestinalnog krvarenja u odjelu hitne medicine
• Author: Marko Alavanja
• Mentor: Neven Baršić (mentor)
• Committee member: Neven Baršić (predsjednik povjerenstva)
• Committee member: Tomislav Meštrović (član povjerenstva)
• Committee member: Marko Brinar (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Emergency Medicine

Abstract

Gastrointestinal bleeding remains a significant cause of morbidity and mortality worldwide, and contributes significantly to health care costs. GI bleeding can be life threatening, and treatment of this condition remains a significant challenge. Mortality rates have persisted stubbornly for decades; however recent advances in guidelines, pre-endoscopic management, and endoscopic therapies has decreased the death rate for this condition. Gastrointestinal bleeding is commonly divided into upper and lower GI bleeding based on the location of the bleed in relation to the ligament of Treitz. Although expansive, this review seeks to succinctly explain the causes, clinical manifestations, and management of both upper and lower gastrointestinal bleeding. A brief discussion of the challenges and uncertainties physicians continue to face concludes this review.

Abstract (croatian)

Krvarenje iz probavnog trakta ostaje važan uzrok morbiditeta i mortaliteta diljem svijeta, te značajno doprinosi visokim troškovima zdravstvene skrbi. Ta vrsta krvarenja može često biti životno ugrožavajuća, a liječenje bolesnika s ovim stanjem ostaje i dalje značajan izazov. Stope smrtnosti su kod gastrointestinalnog krvarenja desetljećima uporno ostajale iste, no relativno recentnim pomacima u endoskopskom i medikamentoznom liječenju te razvojem smjernica prati se smanjenje mortaliteta kod ovih bolesnika. Krvarenje iz probavnog trakta obično se dijeli na krvarenje iz gornjeg i krvarenje iz donjeg trakta, na osnovu lokalizacije mjesta krvarenja u odnosu na Treitzov ligament. Iako opsežan, ovaj pregledni tekst nastoji sažeto obraditi uzroke, kliničke manifestacije i liječenje krvarenja iz oba dijela probavnog trakta. Pregled završava kratkom diskusijom o izazovima i nedoumicama s kojima se liječnici i dalje suočavaju pri zbrinjavanju ovih stanja.

• Keywords: gastrointestinal bleeding; melena; hematochezia; hematemesis; upper GI bleeding; lower GI bleeding
• Keywords (croatian): gastrointestinalno krvarenje; melena; hematokezija; hematemeza; krvarenje iz gornjeg probavnog trakta; krvarenje iz donjeg probavnog trakta
• Language: english
• URN:NBN: urn:nbn:hr:105:666158
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-07-20 09:38:38