Electric conductivity of deoxyribonucleic acid water solutions

master's thesis

• Title (croatian): Električna vodljivost vodenih otopina deoksiribonukleinske kiseline
• Author: Marko Stručić
• Mentor: Sanja Dolanski-Babić (mentor)
• Committee member: Sanja Dolanski-Babić (predsjednik povjerenstva)
• Committee member: Ozren Gamulin (član povjerenstva)
• Committee member: Ljiljana Šerman (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Physics and Biophysics); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Basic Medical Sciences; Medical Biochemistry

Abstract

Deoxyribonucleic acids (DNA) are one of most important naturally occurring macromolecules. Today we know that this molecule is present in every living being carrying its genetic code that defines its species, gender, physical attributes and more. Modern research has come as far as using artificially constructed DNA even in nanotechnology making understanding of its properties
evermore important. From its structure one can observe DNA as a polymeric structure and thus attributing it with general properties from this group. In the past models that simulate polymer behaviour were described one of which is Manning Oosawa condensation model, widely accepted for polyelectrolytes dissolved in water. From this model equations for solution conductivity can be derived. This dissertation compares this calculations with experimental measurements.

Abstract (croatian)

Deoksiribonukleinska kiselina (DNA) je jedna od najvažnijih makromolekula u prirodi. Prema današnjim saznanjima DNA molekula je prisutna u stanicama svakog živog bića, a nosi genetski kod čime definira vrstu, spol, fizička obilježja i mnoge druge karakteristike. Najnovija istraživanja pokazala su već da je moguća proizvodnja DNA, kakva se se koristi u nanotehnologiji. Promatrajući strukturu DNA kao polimernu strukturu mogu joj se dodjeliti opće karakteristike navedene grupe. Povijesno su bili opisani modeli koji simuliraju ponašanje polimera među kojima se nalazi i Manning – Oosawa kondenzacijski model, koji opisuje vodene otopine polielektrolita. Iz tog modela proizlaze jednadžbe koje koreliraju koncentracju istovrsnih otopina s njihovom vodljivošću. Ovaj diplomski rad uspoređuje te izračune s eksperimentalnim mjerenjima.

• Keywords: DNA; conductivity; DNA solutions; Manning Oosawa model
• Keywords (croatian): DNA; vodljivost; DNA otopine; Manning Oosawa model
• Language: english
• URN:NBN: urn:nbn:hr:105:697592
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-07-20 10:50:59