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Scientific paper - Review paper
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
Cells, 8 (2019), 11; 1459. https://doi.org/10.3390/cells8111459
Karin-Kujundžić, Valentina; Šola, Ida Marija; Predavec, Nina; Potonjak, Anamarija; Somen, Ema; Mioč, Pavao; Šerman, Alan; Vranić, Semir; Šerman, Ljiljana

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Karin Kujundžić, V., Šola, I. M., Predavec, N., Potonjak, A., Somen, E., Mioč, P. ... Šerman, Lj. (2019). Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers. Cells, 8. (11). doi: 10.3390/cells8111459

Karin Kujundžić, Valentina, et al. "Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers." Cells, vol. 8, no. 11, 2019. https://doi.org/10.3390/cells8111459

Karin Kujundžić, Valentina, Ida Marija Šola, Nina Predavec, Anamarija Potonjak, Ema Somen, Pavao Mioč, Alan Šerman, Semir Vranić and Ljiljana Šerman. "Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers." Cells 8, no. 11 (2019). https://doi.org/10.3390/cells8111459

Karin Kujundžić, V., et al. (2019) 'Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers', Cells, 8(11). doi: 10.3390/cells8111459

Karin Kujundžić V, Šola IM, Predavec N, Potonjak A, Somen E, Mioč P, and sur.. Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers. Cells [Internet]. 2019 November 18 [cited 2024 November 29];8(11). doi: 10.3390/cells8111459

V. Karin Kujundžić, et al., "Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers", Cells, vol. 8, no. 11, November 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:486765. [Accessed: 29 November 2024]

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Metadata
Title (english)Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
AuthorValentina Karin-Kujundžić
AuthorIda Marija Šola
AuthorNina Predavec
AuthorAnamarija Potonjak
AuthorEma Somen
AuthorPavao Mioč
AuthorAlan Šerman
AuthorSemir Vranić
AuthorLjiljana Šerman
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Biology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Cytology, Histology and Embryology
Abstract (english)
As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders. These studies have enabled the development of various new diagnostic biomarkers, such as free circulating nucleic acids, and detection of their epigenetic changes. Recently, extracellular vesicles including exosomes, microvesicles, oncosomes, and apoptotic bodies have been recognized as powerful diagnostic tools. Extracellular vesicles carry specific proteins, lipids, DNAs, mRNAs, and miRNAs of the cells that produced them, thus reflecting the function of these cells. It is believed that exosomes, in particular, may be the optimal biomarkers of pathological pregnancies and cancers, especially those that are frequently diagnosed at an advanced stage, such as ovarian cancer. In the present review, we survey and critically appraise novel epigenetic biomarkers related to free circulating nucleic acids and extracellular vesicles, focusing especially on their status in trophoblasts (pregnancy) and neoplastic cells (cancers).
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCells
Numberingvol. 8, no. 11, 1459
e-ISSN2073-4409
DOIhttps://doi.org/10.3390/cells8111459
URN:NBNurn:nbn:hr:105:486765
Publication2019-11-18
Document URLhttps://www.mdpi.com/2073-4409/8/11/1459
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2020-12-07 08:28:08