prikaz prve stranice dokumenta Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma
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Scientific paper - Original scientific paper
Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma
Clinical Endocrinology, 93 (2020), 4; 404-408. https://doi.org/10.1111/cen.14251
Kaštelan, Darko; Knežević, Nikola; Zibar Tomšić, Karin; Alduk, Ana‐Marija; Kakarigi, Luka; Kaštelan, Marko; Ćorić, Marijana; Škorić‐Polovina, Tanja; Solak, Mirsala; Kraljević, Ivana; Balasko, Annemarie; Gnjidić, Milena; Dušek, Tina

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Kaštelan, D., Knežević, N., Zibar Tomšić, K., Alduk, A., Kakarigi, L., Kaštelan, M. ... Dušek, T. (2020). Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma. Clinical Endocrinology, 93. (4), 404-408. doi: 10.1111/cen.14251

Kaštelan, Darko, et al. "Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma." Clinical Endocrinology, vol. 93, no. 4, 2020, pp. 404-408. https://doi.org/10.1111/cen.14251

Kaštelan, Darko, Nikola Knežević, Karin Zibar Tomšić, Ana‐Marija Alduk, Luka Kakarigi, Marko Kaštelan, Marijana Ćorić, et al. "Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma." Clinical Endocrinology 93, no. 4 (2020): 404-408. https://doi.org/10.1111/cen.14251

Kaštelan, D., et al. (2020) 'Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma', Clinical Endocrinology, 93(4), pp. 404-408. doi: 10.1111/cen.14251

Kaštelan D, Knežević N, Zibar Tomšić K, Alduk A, Kakarigi L, Kaštelan M, and sur.. Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma. Clinical Endocrinology [Internet]. 2020 October [cited 2024 April 20];93(4):404-408. doi: 10.1111/cen.14251

D. Kaštelan, et al., "Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma", Clinical Endocrinology, vol. 93, no. 4, pp. 404-408, October 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:722674. [Accessed: 20 April 2024]

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Metadata
Title (english)Open vs laparoscopic adrenalectomy for localized adrenocortical carcinoma
AuthorDarko Kaštelan
AuthorNikola Knežević
AuthorKarin Zibar Tomšić
AuthorAna‐Marija Alduk
AuthorLuka Kakarigi
AuthorMarko Kaštelan
AuthorMarijana Ćorić
AuthorTanja Škorić‐Polovina
AuthorMirsala Solak
AuthorIvana Kraljević
AuthorAnnemarie Balasko
AuthorMilena Gnjidić
AuthorTina Dušek
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Objective: The purpose of the study was to compare the long-term outcomes of patients with localized adrenocortical carcinoma (ACC) subjected to open vs laparoscopic surgery. ----- Design: Retrospective study. ----- Patients: This retrospective study included 46 patients with the ACC ENSAT stage I-stage III of whom 23 underwent open surgery (OA group), whereas 23 were subjected to laparoscopic adrenalectomy (LA group). The main outcomes analysed in the study were differences between the OA and LA groups in recurrence-free survival (RFS) and overall survival (OS). ----- Results: Patients in OA group had larger tumours (120 [70-250] mm vs 75 [26-110] mm; P < .001), higher Ki-67 index (16 [1-65] % vs 10 [1-25] %; P = .04) and higher disease stage (P = .01) compared with the patients in the LA group. The median duration of follow-up for patients underwent OA and LA was 51 (12-174) and 53 (5-127) months, respectively. Eight patients (5 OA and 3 LA) experienced recurrent disease, whereas six patients (3 OA and 3 LA) died during follow-up. No differences in RFS and OS were found between patients who underwent open or laparoscopic surgery. ----- Conclusion: The study demonstrated that in patients with localized ACC and without invasion of extra-adrenal tissues, LA is a plausible treatment option in terms of RFS and OS. However, our results are limited to referral centres with large experience in the management of patients with ACC and may not necessarily apply to nonspecialized centres.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleClinical Endocrinology
Numberingvol. 93, no. 4, pp. 404-408
p-ISSN0300-0664
e-ISSN1365-2265
DOIhttps://doi.org/10.1111/cen.14251
URN:NBNurn:nbn:hr:105:722674
Publication2020-10
Document URLhttps://onlinelibrary.wiley.com/doi/10.1111/cen.14251
Type of resourceText
Access conditionsOpen access
Embargo expiration date: 2021-11-01
Terms of useLicence In copyright icon
Created on2021-04-21 10:56:18