prikaz prve stranice dokumenta Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center
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Scientific paper - Original scientific paper
Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center
Archives of Gynecology and Obstetrics, 301 (2020), 5; 1227-1233. https://doi.org/10.1007/s00404-020-05522-5
Mikuš, Mislav; Benco, Nikolina; Matak, Luka; Planinić, Pavao; Ćorić, Mario; Lovrić, Helena; Radošević, Velena; Puževski, Tomislav; Bajt, Mirna; Vujić, Goran

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Mikuš, M., Benco, N., Matak, L., Planinić, P., Ćorić, M., Lovrić, H. ... Vujić, G. (2020). Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center. Archives of Gynecology and Obstetrics, 301. (5), 1227-1233. doi: 10.1007/s00404-020-05522-5

Mikuš, Mislav, et al. "Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center." Archives of Gynecology and Obstetrics, vol. 301, no. 5, 2020, pp. 1227-1233. https://doi.org/10.1007/s00404-020-05522-5

Mikuš, Mislav, Nikolina Benco, Luka Matak, Pavao Planinić, Mario Ćorić, Helena Lovrić, Velena Radošević, Tomislav Puževski, Mirna Bajt and Goran Vujić. "Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center." Archives of Gynecology and Obstetrics 301, no. 5 (2020): 1227-1233. https://doi.org/10.1007/s00404-020-05522-5

Mikuš, M., et al. (2020) 'Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center', Archives of Gynecology and Obstetrics, 301(5), pp. 1227-1233. doi: 10.1007/s00404-020-05522-5

Mikuš M, Benco N, Matak L, Planinić P, Ćorić M, Lovrić H, and sur.. Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center. Archives of Gynecology and Obstetrics [Internet]. 2020 May [cited 2024 April 11];301(5):1227-1233. doi: 10.1007/s00404-020-05522-5

M. Mikuš, et al., "Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center", Archives of Gynecology and Obstetrics, vol. 301, no. 5, pp. 1227-1233, May 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:015670. [Accessed: 11 April 2024]

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Metadata
Title (english)Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center
AuthorMislav Mikuš
AuthorNikolina Benco
AuthorLuka Matak
AuthorPavao Planinić
AuthorMario Ćorić
AuthorHelena Lovrić
AuthorVelena Radošević
AuthorTomislav Puževski
AuthorMirna Bajt
AuthorGoran Vujić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Gynecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
Purpose: To describe a case series of patients with malignant ovarian germ cell tumors (MOGCT) treated exclusively with fertility-sparing surgery (FSS) with or without adjuvant chemotherapy. ----- Methods: We retrospectively reviewed the records of 27 patients with MOGCT treated in the Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Croatia, between January 2009 and July 2019. ----- Results: The median age at diagnosis was 22 years, and the main symptom was abdominal distension (57.0%). The most prevalent histological subtype was immature teratoma (n = 13, 48.1%). Twenty-three patients (85.2%) had laparotomy and 4 (14.8%) had laparoscopy, without conversions. Lymphadenectomy was performed in 16 (59.3%) patients, with 184 removed lymph nodes, and omentectomy was performed in 19 (70.4%) patients. The rate of chemotherapy administration was 81.5%. The follow-up length ranged between 6.30 and 115.1 months (median: 49.60 months). No patient experienced tumor recurrence. The rate of complete gross resection was 100%. At the time of analysis, all patients were alive and disease free. Fifty percent of patients who actively tried to conceive after FSS became pregnant, with 12 deliveries. ----- Conclusion: This study suggests that FSS is a safe treatment option for MOGCT, regardless of tumor stage and histological type.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleArchives of Gynecology and Obstetrics
Numberingvol. 301, no. 5, pp. 1227-1233
p-ISSN0932-0067
e-ISSN1432-0711
DOIhttps://doi.org/10.1007/s00404-020-05522-5
URN:NBNurn:nbn:hr:105:015670
Publication2020-05
Document URLhttp://link.springer.com/10.1007/s00404-020-05522-5
Type of resourceText
Access conditionsOpen access
Embargo expiration date: 2021-06-01
Terms of useLicence In copyright icon
Created on2021-04-21 14:02:44