Usporedba preoperativne ultrazvučne, intraoperativne i patohistološke podudarnosti dijagnoze polipa žučnjaka

master's thesis

• Title (english): Comparison of preoperative ultrasound, intraoperative, and histopathological compatibility of gallbladder polyp diagnosis
• Author: Lucija Brkić
• Mentor: Goran Augustin (mentor)
• Committee member: Hrvoje Silovski (predsjednik povjerenstva)
• Committee member: Tomislav Meštrović (član povjerenstva)
• Committee member: Goran Augustin (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Surgery); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Surgery

Abstract

UVOD:Kolecistektomija je jedna od najčešće izvođenih operacija abdominalne kirurgije. Najčešće indikacije su bilijarna diskinezija, simptomatska kolelitijaza te akutni i kronični kolecistitis. U slučaju da se ultrazvučnim pregledom abdomena otkrije polip žučnjaka, ovisno o njegovoj veličini preporuča se redovito praćenje ili kolecistektomija, zbog moguće maligne alteracije. Hipoteza istraživanja je da je većina polipa otkrivenih ultrazvučnim pregledom u stvarnosti manji kolelit ili gusta žuč. ----- CILJ: Cilj istraživanja je usporediti podudarnost ultrazvučnog, intraoperativnog i patohistološkog nalaza polipa žučnjaka i utvrditi učestalost polipa žučnjaka u promatranom uzorku. ----- ISPITANICI I METODE: Retrospektivnom analizom svih kolecistektomija u tercijarnoj ustanovi u periodu od pet godina uspoređene su ultrazvučne, intraoperativne i patohistološke dijagnoze polipa žučnog mjehura. Matične liste, nalazi ultrazvuka, operacijske liste i patohistološki nalazi pregledani su i prikupljeni traženi podaci. ----- REZULTATI: Primarni uzorak činilo je 3651 bolesnika. Primjenom kriterija isključenja utvrđen je konačni uzorak od 3445 bolesnika. Ultrazvučnim pregledom polip je zabilježen u 206 (5.97%) slučajeva, makroskopskim intraoperativnim pregledom operateri su zabilježili 46 (1.33%) polipa, dok je 7 (0.20%) polipa potvrđeno patohistološkim pregledom. ----- ZAKLJUČAK: Ultrazvučni, intraoperativni i postoperativni nalaz polipa žučnog mjehura vrlo su malo podudarni te je učestalost polipa žučnog mjehura u promatranom uzorku niska.

Abstract (english)

INTRODUCTION: Cholecystectomy is one of the most commonly performed abdominal surgery operations. The most common indications are biliary dyskinesia, symptomatic cholelithiasis, and acute or chronic cholecystitis. If ultrasound examination of the abdomen reveals a gallbladder polyp, regular monitoring or cholecystectomy is recommended, depending on its size and possibility of malignant alteration. The research hypothesis is that the majority of polyps detected by ultrasound examination are in fact smaller coleliths or thick bile. ----- AIM:The aim of the study is to compare whether ultrasonographic, intraoperative and pathohistological findings of gallbladder polyps correlate with each other and determine the frequency of gallbladder polyps in the observed sample. ----- SUBJECTS AN METHODS: A retrospective analysis of all cholecystectomies in a tertiary institution over a five-year period compared ultrasonographic, intraoperative, and pathohistological diagnoses of gallbladder polyps. Registers, ultrasound findings, surgery lists and histopathological findings were reviewed and the required data were collected. ----- RESULTS: The primary sample consisted of 3651 patients. A final sample of 3445 patients was determined after applying the exclusion criteria. Ultrasound examination revealed polyps in 206 (5.97%) cases, macroscopic intraoperative examination revealed 46 (1.33%) polyps, and 7 (0.20%) polyps were confirmed by histopathological examination. ----- CONCLUSION: Ultrasonographical, intraoperative and postoperative pathohistological diagnosis of gallbladder polyps widely differ and the frequency of gallbladder polyps in the observed sample is low.

• Keywords: žučni mjehur; bolesti žučnog mjehura; kolecistektomija; neoplazme žučnog mjehura
• Keywords (english): gallbladder; gallbladder diseases; cholecystectomy; gallbladder neoplasm
• Language: croatian
• URN:NBN: urn:nbn:hr:105:637681
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-07-30 07:43:45