Usporedba nalaza pri kiretaži i konačnog PHD nalaza u bolesnica s karcinomom endometrija

master's thesis

• Title (english): Comparison of pathohistological findings obtained by curettage and hysterectomy in patients with endometrial cancer
• Author: Sandra Tipurić
• Mentor: Joško Lešin (mentor)
• Committee member: Goran Vujić (predsjednik povjerenstva)
• Committee member: Dinka Pavičić Baldani (član povjerenstva)
• Committee member: Joško Lešin (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Gynecology and Obstetrics); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Oncology

Abstract

CILJ: Ispitati podudarnost nalaza pri kiretaži i konačnog PHD nalaza u bolesnica sa sumnjom na karcinom endometrija. ----- MATERIJAL I METODE: U istraživanje je bilo uključeno 100 pacijentica sa sumnjom na karcinom endometrija koje su liječene u Klinici za ženske bolesti KBC-a Zagreb 2016. godine. Podaci su prikupljeni iz medicinske dokumentacije bolničkog informatičkog sustava. Obrađeni su anamnestički podaci pacijentica te patohistološki nalazi kiretmana i konačnog PHD nalaza nakon histerektomije. ----- REZULTATI: Istraživanje je pokazalo da je dijagnostička nepodudarnost između nalaza kiretmana i patohistološkog nalaza u 31 pacijentice, dok se nalaz podudara u 68 pacijentica. Jedna pacijentica nije imala nalaz kiretmana te nije bila moguća usporedba, što znači da su uspoređeni nalazi 99 pacijentica. Izračunom dobivamo da je nepodudarnost nalaza u 31,31% slučajeva. ----- ZAKLJUČAK: Frakcionirana kiretaža je najvažniji dijagnostički postupak za dijagnosticiranje karcinoma endometrija. Budući da je količina dobivenog materijala različita, postoje i određena odstupanja u PHD nalazu kiretmana i konačnom PHD nalazu histerektomije. Zbog toga treba napraviti i drugu obradu koji će povećati preciznost predoperacijske dijagnostike.

Abstract (english)

OBJECTIVES: To determine compatibility rate between histological grades and types of endometrial carcinoma. The speciment was obtained by curretage and hysterectomy. ----- MATERIAL AND METHODS: The study included 100 patients with suspected endometrial cancer who were treated at the Clinic for Women's Diseases of the University Hospital Center Zagreb in 2016. Data were collected from the medical records of the hospital information system. Patients' anamnestic data and pathohistological findings of curettage and final pathohistological findings after hysterectomy were processed. ----- RESULTS: The study showed that there was a diagnostic discrepancy between the curettage findings and the pathohistological finding in 31 patients, while the finding matched in 68 patients. One patient did not have a curettage finding and no comparison was possible, which means that the findings of 99 patients were compared. The calculated discrepancy of the findings is in 31.31% of cases. ----- CONCLUSIONS: Fractional curettage is the most important diagnostic procedure for diagnosing endometrial cancer. Since the amount of material obtained is different, there are also some discrepancies in the PHD finding of the curettage and the final PHD finding of the hysterectomy. Therefore, another treatment should be done that will increase the accuracy of preoperative diagnostics.

• Keywords: karcinom endometrija; frakcionirana kiretaža; histološki gradus; histerektomija
• Keywords (english): endometrial cancer; fractional curettage; histological grade; hysterectomy
• Language: croatian
• URN:NBN: urn:nbn:hr:105:797517
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-07-30 09:16:05