Drug prescribing in older patients

master's thesis

• Title (croatian): Primjena lijekova u pacijenata starije životne dobi
• Author: Marko Luka Bošković
• Mentor: Robert Likić (mentor)
• Committee member: Hrvoje Tiljak (predsjednik povjerenstva)
• Committee member: Robert Likić (član povjerenstva)
• Committee member: Jasenka Markeljević (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Clinical Pharmacology and Toxicology
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Poor prescribing is a common occurrence, notably relevant in settings with at-risk patients. Patients with multiple comorbidities require multiple drug therapies, establishing fertile soil for the manifestation of adverse drug events. As organ function decreases in older patients, drug doses oftentimes are failed to be prescribed at an appropriate level. The combination of elevated doses and unnecessary prescriptions puts endangered patients at further risk for developing avoidable adverse events. In order to protect vulnerable patients, strides must be taken towards appropriate prescribing and dosing. When the focus of treatment is clear with defined goals, we can aim at providing a suitable regimen which adds life to the remaining years of our patients.

Abstract (croatian)

Neefikasno propisivanje lijekova uobičajena je pojava, osobito relevantna u okruženjima s rizičnim pacijentima. Bolesnici s više komorbiditeta zahtijevaju višestruke terapije lijekovima, uspostavljajući plodno tlo za utjecaj štetnih lijekova. Kako opada funkcija organa kod starijih bolesnika, doze lijekova često se ne propisuju na odgovarajućoj razini. Kombinacija povišenih doza i nepotrebnih recepata stavlja ugrožene pacijente u daljnji rizik kod razvoja nuspojava koje se mogu izbjeći. Da bi se zaštitili ranjivi pacijenti, potrebno je poduzeti korake prema odgovarajućem propisivanju i doziranju. Kad je fokus liječenja jasan sa definiranim ciljevima, možemo se usmjeriti na pružanje odgovarajućeg režima koji će dodati život ostalim godinama našim pacijentima.

• Keywords: prescribing; polypharmacy; adverse drug events; geriatrics
• Keywords (croatian): propisivanje; polifarmacija; štetni događaji lijekova; gerijatrija
• Language: english
• URN:NBN: urn:nbn:hr:105:588706
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-10-01 10:24:00