The usage of antibiotics in bone surgery

master's thesis

• Author: Patrick Julien Bernard Tschechne
• Mentor: Goran Bićanić (mentor)
• Committee member: Domagoj Delimar (predsjednik povjerenstva)
• Committee member: Tomislav Meštrović (član povjerenstva)
• Committee member: Goran Bićanić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Orthopedics); Zagreb
• Defense date and country: 2014-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Orthopedics

Abstract

The discovery of antibiotics has drastically changed modern medicine and everyday human life. Even though extraordinary discoveries have been made perioperative infections are still commonly encountered in clinical practice. Deep infections such as septic arthritis, osteomyelitis and periprosthetic joint infections pose great difficulties to practising surgeons and increase the financial burden for health care systems across the globe. Multiple antibiotic regimens are commonly used where bone surgery is performed. Cephalosporins such as cefazolin are routinely administered in surgical theatres around the world, as a measure of prophylaxis to surgical site infections. Nevertheless other antibiotics are also frequently indicated. Due to a rise in multidrug-resistant micro-organisms worldwide, glycopeptide administration has over time increased markedly. For instance vancomycin may nowadays be used in clinical settings where methicillin-resistant Staph. aureus (MRSA) is often encountered. Despite existing clinical guidelines, research is still needed to keepthe surgical community up-to-date during the combat of perioperative infections.

• Keywords: Antibiotics; Bone Surgery; Perioperative Surgical Prophylaxis; Surgical Site Infections; MRSA
• Language: english
• URN:NBN: urn:nbn:hr:105:075461
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-12-03 13:05:05