Postupci medicinski pomognute oplodnje

master's thesis

• Title (english): Methods of medically assisted reproduction
• Author: Lea Valenčić
• Mentor: Doroteja Pavan-Jukić (mentor)
• Committee member: Lana Škrgatić (predsjednik povjerenstva)
• Committee member: Željko Duić (član povjerenstva)
• Committee member: Doroteja Pavan-Jukić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Gynecology and Obstetrics); Zagreb
• Defense date and country: 2021-07-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics

Abstract

Medicinski pomognuta oplodnja (MPO) obuhvaća skup metoda za liječenje neplodnosti jednog ili oba partnera. To su kliničke i laboratorijske tehnologije kojima se postiže oplodnja i trudnoća kada svi ostali oblici liječenja postanu neučinkoviti. Neplodnost je postala velik javnozdravstveni i populacijski problem, a glavni uzroci neplodnosti su dob žene i muškarca, odgađanje roditeljstva te brojni čimbenici povezani s načinom života. Razumijevanje regulacije reproduktivnog sustava i napredne metode dijagnosticiranja i liječenja neplodnosti omogućile su brojnim parovima postizanje kliničke trudnoće i rađanje zdravog djeteta. Medicinski pomognuta oplodnja u Hrvatskoj je regulirana zakonom kojim su određeni uvjeti, prava, obveze i odgovornosti svih sudionika tih postupaka. Metode MPO koje se najčešće koriste su IUI - intrauterina inseminacija, ITI - intratubarna inseminacija, IVF - in vitro fertilizacija i ICSI – intracitoplazmatska injekcija spermija. Ostali postupci koji se rade su unos gameta, zigote ili embrija u jajovod (GIFT, ZIFT, TET) i krioprezervacija sjemena, jajnih stanica ili zametaka za buduću oplodnju. Metodama MPO liječi se 70 do 80% svih uzroka neplodnosti, a svakom postupku mora prethoditi individualizirani pristup i kvalitetna obrada kako bi se rizici i komplikacije sveli na najmanju moguću razinu.

Abstract (english)

Assisted reproductive technology involves a set of methods to treat the infertility in one or both partners. These are clinical and laboratory technologies that achieve fertilization and pregnancy when all other forms of treatment become ineffective. Infertility has become a major population and public health problem. The main causes of infertility are the high age of female and male partner, delayed parenthood, and a number of lifestyle-related factors. Understanding the regulation of the reproductive system and advanced methods of diagnosing and treating infertility, enables many couples to achieve clinical pregnancies and give birth to a healthy child. In Croatia, medically assisted reproduction is regulated by law, which determines the conditions, rights, obligations and responsibilities of all participants in these procedures. The most commonly used methods of medically assisted reproduction are IUI - intrauterine insemination, ITI - intratubal insemination, IVF - in vitro fertilization and ICSI - intracytoplasmic sperm injection. Other procedures that are performed are the insertion of gametes, zygotes or embryos into the fallopian tube (GIFT, ZIFT, and TET) and cryopreservation of semen, eggs or embryos for future fertilization. ART treats 70 to 80% of all causes of infertility, and each procedure must be preceded by an individualized approach and quality treatment to minimize risks and complications.

• Keywords: MPO; medicinski pomognuta oplodnja; metode; neplodnost; IUI; intrauterina inseminacija; ITI; intratubarna inseminacija; IVF; in vitro fertilizacija; ICSI; intracitoplazmatska injekcija spermija; krioprezervacija
• Keywords (english): ART; assisted reproductive technology; methods; infertility; IUI; intrauterine insemination; ITI; intratubal insemination; IVF; in vitro fertilization; ICSI; intracytoplasmic sperm injection; cryopreservation
• Language: croatian
• URN:NBN: urn:nbn:hr:105:017492
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-05-19 07:37:16