Stereotaksijska, vakuumom asistirana biopsija dojke

master's thesis

• Title (english): Vacuum-assisted stereotactic breast biopsy
• Author: Mirna Vučemilo
• Mentor: Maja Prutki (mentor)
• Committee member: Maja Hrabak Paar (predsjednik povjerenstva)
• Committee member: Gordana Ivanac (član povjerenstva)
• Committee member: Maja Prutki (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Radiology); Zagreb
• Defense date and country: 2021-07-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Radiology

Abstract

Rak dojke najčešći je tumor i treći po redu maligni uzrok smrti u žena. Osnovne radiološke pretrage za dijagnostiku bolesti dojke su mamografija, ultrazvuk i magnetska rezonancija. Postoje razne benigne promjene koje mogu oponašati malignost na svim metodama snimanja dojke. Zato je važan korak u dijagnostici biopsija dojke. Bioptirano tkivo patohistološki se analizira kako bi se postavila konačna dijagnoza. Perkutana biopsija dojke razvila se kao alternativa kirurškoj biopsiji. To je minimalno invazivni postupak koji smanjuje troškove dijagnostike i pošteđuje pacijentice od nepotrebnog kirurškog zahvata patohistološki potvrđene benigne lezije. Vakuumom asistirana biopsija (VAB) omogućuje uzimanje većeg broja uzoraka uzastopno bez uklanjanja igle. VAB se obično izvodi navođenjem pod kontrolom mamografije ili tomosinteze. Stereotaksijska vakuumoma asistirana biopsija (SVAB) je biopsija dojke navođena mamografijom. Stereotaksija zahtijeva snimanje početne i dviju dodatnih snimki s jednakim stupnjem zakrivljenosti u odnosu na početnu snimku pri čemu se dobivaju koordinate koje određuju lokalizaciju ciljane lezije. SVAB je minimalno invazivan i precizan postupak za dijagnozu mikrokalcifikata dojke otkrivenih mamografijom. Ova tehnika pruža visokokvalitetne uzorke, visoku stopu uzorkovanja kalcifikata i nisku lažno negativnu stopu, što ju čini metodom izbora u dijagnostici mikrokalcifikata dojke.

Abstract (english)

The breast cancer is the most common tumor and the third malignant cause of death in women. Mammography, ultrasound and magnetic resonance are frequently used in the breast imaging. There are a variety of benign abnormalities which can mimic malignancy on all breast imaging modalities. Therefore, a breast biopsy has the key role in making a definitive diagnosis. Tissue samples are used in the pathohistological analysis to define the exact type of the lesion. Percutaneous breast biopsy has been developed as an alternative method of surgical breast biopsy. It is a minimally invasive procedure that saves us from diagnostic cost and patients from unnecessary surgical procedure of pathohistologically confirmed benign lesion. Vacuum assisted biopsy (VAB) provides taking multiple samples continuously without removing the needle. The VAB is usually performed under mammography or tomosynthesis guidance. Stereotactic vacuum assisted biopsy (SVAB) is mammography guided breast biopsy. SVAB is a minimally invasive and accurate procedure for the diagnosis of breast microcalcifications detected by mammography. This technique involves high-quality specimens, a high calcification retrieval rate, and a low false-negative rate, making it a preferred type of diagnostic method of breast microcalcifications.

• Keywords: stereotaksijska vakuumom asistirana biopsija; rak dojke; biopsija dojke; mikrokalcifikati; mamografija
• Keywords (english): vacuum-assisted stereotactic biopsy; breast cancer; breast biopsy; microcalcifications; mammography
• Language: croatian
• URN:NBN: urn:nbn:hr:105:301787
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-05-20 08:20:26