Borderline resectable pancreatic cancer and vascular resections in the era of neoadjuvant therapy

Scientific paper - Review paper

• Author: Danko Mikulić
• Author: Anna Mrzljak
• Author's institution: University of Zagreb; School of Medicine; (Department of Internal Medicine)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract (english)

While pancreatic cancer is still characterized by early systemic spread and poor outcomes, the treatment of this disease has changed significantly in recent years due to major advancements in systemic therapy and advanced surgical techniques. Broader use of effective neoadjuvant approaches combined with aggressive surgical operations within a multidisciplinary setting has improved outcomes. Borderline resectable pancreatic cancer is characterized by tumor vascular invasion, and is a setting where the combination of potent neoadjuvant chemotherapy and aggressive surgical methods, including vascular resections and reconstructions, shows its full potential. Hopefully, this will lead to improved local control and curative treatment in a number of patients with this aggressive malignancy.

• Keywords (english): Arterial resection; Borderline resectable; Neoadjuvant therapy; Pancreatic adenocarcinoma; Vascular reconstruction; Venous resection
• Language: english
• Publication type: Scientific paper - Review paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: World Journal of Clinical Cases
• Numbering: vol. 9, no. 20, pp. 5398-5407
• e-ISSN: 2307-8960
• DOI: https://doi.org/10.12998/wjcc.v9.i20.5398
• URN:NBN: urn:nbn:hr:105:549397
• Publication: 2021-07-16
• Document URL: https://www.wjgnet.com/2307-8960/full/v9/i20/5398.htm
• Type of resource: Text
• Access conditions: Open access
• Created on: 2022-06-02 08:40:12