prikaz prve stranice dokumenta Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies
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Scientific paper - Review paper
Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies
Materials, 14 (2021), 13; 3513. https://doi.org/10.3390/ma14133513
Štoković, Nikola; Ivanjko, Natalia; Matičić, Dražen; Luyten, Frank P.; Vukičević, Slobodan

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Štoković, N., Ivanjko, N., Matičić, D., Luyten, F. P. & Vukičević, S. (2021). Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies. Materials, 14. (13). doi: 10.3390/ma14133513

Štoković, Nikola, et al. "Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies." Materials, vol. 14, no. 13, 2021. https://doi.org/10.3390/ma14133513

Štoković, Nikola, Natalia Ivanjko, Dražen Matičić, Frank P. Luyten and Slobodan Vukičević. "Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies." Materials 14, no. 13 (2021). https://doi.org/10.3390/ma14133513

Štoković, N., et al. (2021) 'Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies', Materials, 14(13). doi: 10.3390/ma14133513

Štoković N, Ivanjko N, Matičić D, Luyten FP, Vukičević S. Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies. Materials [Internet]. 2021 June 24 [cited 2024 December 20];14(13). doi: 10.3390/ma14133513

N. Štoković, N. Ivanjko, D. Matičić, F. P. Luyten and S. Vukičević, "Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies", Materials, vol. 14, no. 13, June 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:423123. [Accessed: 20 December 2024]

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Metadata
Title (english)Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies
AuthorNikola Štoković
AuthorNatalia Ivanjko
AuthorDražen Matičić
AuthorFrank P. Luyten
AuthorSlobodan Vukičević
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Anatomy and Clinical Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Anatomy
Abstract (english)
Bone morphogenetic proteins (BMPs) possess a unique ability to induce new bone formation. Numerous preclinical studies have been conducted to develop novel, BMP-based osteoinductive devices for the management of segmental bone defects and posterolateral spinal fusion (PLF). In these studies, BMPs were combined with a broad range of carriers (natural and synthetic polymers, inorganic materials, and their combinations) and tested in various models in mice, rats, rabbits, dogs, sheep, and non-human primates. In this review, we summarized bone regeneration strategies and animal models used for the initial, intermediate, and advanced evaluation of promising therapeutical solutions for new bone formation and repair. Moreover, in this review, we discuss basic aspects to be considered when planning animal experiments, including anatomical characteristics of the species used, appropriate BMP dosing, duration of the observation period, and sample size.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMaterials
Numberingvol. 14, no. 13, 3513
e-ISSN1996-1944
DOIhttps://doi.org/10.3390/ma14133513
URN:NBNurn:nbn:hr:105:423123
Publication2021-06-24
ProjectNumber: KK.01.1.1.01.0008
Title (croatian): Znanstveni centar izvrsnosti za reproduktivnu i regenerativnu medicinu – istraživanja novih platformi i potencijala
Leader: Slobodan Vukičević
Jurisdiction: eu
Document URLhttps://www.mdpi.com/1996-1944/14/13/3513
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-06-15 11:11:01