prikaz prve stranice dokumenta High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?
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Scientific paper - Original scientific paper
High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?
International Urology and Nephrology, 54 (2022), 8; 1995-2004. https://doi.org/10.1007/s11255-021-03092-2
Premužić, Vedran; Gardijan, Danilo; Herega, Tomislav; Perkov, Dražen; Jelaković, Bojan

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Premužić, V., Gardijan, D., Herega, T., Perkov, D. & Jelaković, B. (2022). High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?. International Urology and Nephrology, 54. (8), 1995-2004. doi: 10.1007/s11255-021-03092-2

Premužić, Vedran, et al. "High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?." International Urology and Nephrology, vol. 54, no. 8, 2022, pp. 1995-2004. https://doi.org/10.1007/s11255-021-03092-2

Premužić, Vedran, Danilo Gardijan, Tomislav Herega, Dražen Perkov and Bojan Jelaković. "High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?." International Urology and Nephrology 54, no. 8 (2022): 1995-2004. https://doi.org/10.1007/s11255-021-03092-2

Premužić, V., et al. (2022) 'High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?', International Urology and Nephrology, 54(8), pp. 1995-2004. doi: 10.1007/s11255-021-03092-2

Premužić V, Gardijan D, Herega T, Perkov D, Jelaković B. High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?. International Urology and Nephrology [Internet]. 2022 August [cited 2024 December 20];54(8):1995-2004. doi: 10.1007/s11255-021-03092-2

V. Premužić, D. Gardijan, T. Herega, D. Perkov and B. Jelaković, "High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?", International Urology and Nephrology, vol. 54, no. 8, pp. 1995-2004, August 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:494856. [Accessed: 20 December 2024]

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Metadata
Title (english)High prevalence of middle cerebral artery calcification is associated with cardiovascular mortality in hemodialyzed patients: an overlooked part of arterial tree?
AuthorVedran Premužić
AuthorDanilo Gardijan
AuthorTomislav Herega
AuthorDražen Perkov
AuthorBojan Jelaković
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Purpose: We have analyzed markers of accelerated atherosclerosis like large artery stiffness, ankle-brachial index, carotid and vertebral duplex ultrasonography and their possible associations with the incidence of intracranial calcifications, clinical course of hemodialyzed patients, and cardiovascular mortality. ----- Methods: A computed tomographic scan of the head was performed for any neurological indication on 100 hemodialyzed patients. Eleven intracranial arteries were analyzed for calcification score, while internal carotid arteries and vertebral arteries were excluded in cerebral artery calcification score. As a control group for assessing intracranial calcifications, we have analyzed computed tomographic scans from diabetic patients who had an acute stroke. ----- Results: Deceased patients had significantly higher values of augmentation index and pulse wave velocity, lower ankle-brachial index, and higher internal carotid arteries peak systolic value than survived patients. Deceased patients had significantly higher number of calcified middle cerebral arteries as well as significantly higher intracranial artery calcification score and cerebral artery calcification score. Hemodialyzed patients had significantly higher both intracranial and cerebral artery calcification scores than diabetic control group. Age and calcified middle cerebral arteries had increased HR of 1.08 and 1.36 for cardiovascular mortality. ----- Conclusion: This study showed that large artery stiffness and not the presence of peripheral arterial disease or carotid artery stenosis have the prognostic role of middle cerebral arteries' calcifications and cardiovascular mortality in hemodialyzed patients. The presence of middle cerebral arteries' calcifications diagnosed by a non-invasive method should be considered a marker of middle-sized conduit arteries atherosclerosis, subclinical brain damage, and future fatal cardiovascular events.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleInternational Urology and Nephrology
Numberingvol. 54, no. 8, pp. 1995-2004
e-ISSN1573-2584
DOIhttps://doi.org/10.1007/s11255-021-03092-2
URN:NBNurn:nbn:hr:105:494856
Publication2022-08
Document URLhttps://link.springer.com/10.1007/s11255-021-03092-2
Type of resourceText
Access conditionsOpen access
Embargo expiration date: 2023-09-01
Terms of useLicence In copyright icon
Created on2022-11-15 10:41:59