Dermatologija u vrijeme pandemije COVID-19

master's thesis

• Title (english): Dermatology during the COVID-19 pandemic
• Author: Rea Deghenghi
• Mentor: Romana Čeović (mentor)
• Committee member: Mihael Skerlev (predsjednik povjerenstva)
• Committee member: Suzana Ljubojević Hadžavdić (član povjerenstva)
• Committee member: Romana Čeović (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Dermatology); Zagreb
• Defense date and country: 2022-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Dermatovenerology

Abstract

Nakon što je krajem 2019. godine novi koronavirus, kasnije nazvan SARS-CoV-2, detektiran u
Kini, munjevitom je brzinom pokorio cijeli svijet. Pandemija je za sobom ostavila mnoge
posljedice: preko 6 milijuna umrlih, socioekonomsku deterioraciju u državama i krizu u
zdravstvenim sustavima. Nova bolest, koju je Svjetska zdravstvena organizacija nazvala COVID-
19, primarno pogađa respiratorni sustav, a do letalnog ishoda vodi teškom pneumonijom s
respiratornim zatajenjem. Postoji široka lepeza manifestacija ove bolesti na drugim organskim
sustavima, a u ovom su radu detaljno opisane pojave iz dermatološkog spektra. Osim mnogih osipa
i lezija na koži, zahvaćeni su i sluznica usne šupljine, nokti i kosa. U novi je način života
implementirano svakodnevno nošenje medicinske zaštitne opreme, u prvome redu maski, koja sa
sobom nosi niz nuspojava na koži i vodi do egzacerbacija dermatoza. Nadalje, izazov
dermatološkoj struci predstavljali su COVID-19 pozitivni pacijenti s kroničnim upalnim
dermatozama na imunomodulatornoj terapiji koja može povećavati rizik za teži klinički tijek i
razvoj kritičnih stanja. Zbog SARS-CoV-2 virusa minimaliziran je i obustavljen rad u
ambulantama i na odjelima, što ima reperkusiju na broj novootkrivenih melanoma i zakašnjele
dijagnoze, a posljedice u vidu porasta mortaliteta vidjet će se tek narednih godina.

Abstract (english)

Near the end of 2019, a new coronavirus was discovered in China, later named SARS-CoV-2. It
spread rapidly throughout the whole world. The aftermath of the pandemic was huge: more than 6
million deaths, global decline of the socioeconomic status and a global health care system crisis.
The new disease, which was named COVID-19 by the World Health Organization, primarily
affects the respiratory system and leads to death by causing severe pneumonia with respiratory
failure. This disease affects other organ systems too, including the integumentary system, which
this paper describes in detail. Besides causing rash and other skin lesions, the virus also affects the
mucosa of the oral cavity, nails and hair. The “new normal” includes wearing personal protective
equipment on a daily basis, primarily masks, which cause a whole new range of cutaneous side
effect. Furthermore, patients on immunomodulatory therapy for chronic skin dermatoses who got
infected with COVID-19 presented yet another challenge for dermatologists, because
immunomodulators may increase the risk of severe disease and worse clinical outcomes. Due to
SARS-CoV-2, normal functioning of the dermatology departments and clinics was impaired,
which consequently caused a rise in morbidity and mortality, presenting an additional burden for
health care systems.

• Keywords: dermatologija; COVID-19; SARS-CoV-2
• Keywords (english): dermatology; COVID-19; SARS-CoV-2
• Language: croatian
• URN:NBN: urn:nbn:hr:105:567546
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-01-05 09:07:59