Kožni tumori uške

master's thesis

• Title (english): Cutaneous tumors of the ear
• Author: Mirella Graffel
• Mentor: Krsto Dawidowsky (mentor)
• Committee member: Romana Čeović (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Krsto Dawidowsky (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery); Zagreb
• Defense date and country: 2022-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract

Uho je zbog svoje anatomske pozicije posebice izloženo suncu i UV-zračenju, koje je predisponirajući čimbenik za razvoj brojnih kožnih lezija. Tanka koža, brojne žlijezde lojnice i znojnice čine uho pogodnim za razvoj invazivnijih oblika kožnih tumora. Nemelanomske tumore kože koje nalazimo na području uške možemo podijeliti na epitelne i neepitelne te maligne i benigne. Najčešći kožni tumori uške su seboroične keratoze, aktinične keratoze te bazocelularni i planocelularni karcinomi. Istraživali smo kožne promjene uške tijekom 5 godina u Kliničkom bolničkom centru u Zagrebu. Od ukupno 147 ispitanika s tumorskim promjenama uške je 108 muškaraca (73,47%) i 39 žena (26,53%). Distribucije po dobi imaju sličan vrhunac pojavnosti kožnih tumora uške, oko 80. godine, pri čemu distribucija u populaciji žena poprima bimodalan karakter sa sekundarnim vrhuncem pojavnosti oko 45. godine. Najviše bolesnika je imalo dijagnozu BCC-a (43 pacijenata), PCC-a (31 pacijent), aktinične keratoze (28 pacijenata), keloida (13 pacijenata), naevusa naevocellularis (9 pacijenata) te seboroične keratoze (8 pacijenata). Metodom krioterapije liječeno je 35 pacijenata, od kojih je 14 imalo recidiv nakon završenog krioterapijskog pristupa (28,57%). Od 112 pacijenata liječenih ekscizijom u 10 je zabilježen recidiv bolesti (8,20%). Iako je pojavnost recidiva nakon kirurškog pristupa manja, svaki pacijent zahtjeva individualizirani i interdisciplinarni pristup (dermatološki, otorinolaringološki i kirurški) kako bi mu se pružila najbolja moguća skrb.

Abstract (english)

Due to its anatomical position, the ear is exposed to the sun and UV radiation, which is a predisposing factor for the development of various cutaneous lesions. Thin skin, numerous sebaceous glands and sweat glands make it suitable for the development of more invasive forms of cutaneous tumors. Non-melanoma cutaneous tumors located in the ear area can be divided into epithelial and non-epithelial, and malignant and benign. The most common cutaneous tumors of the ear are seborrhoeic keratosis, actinic keratosis, basal cell and squamous cell carcinomas. We investigated skin changes of the ear during 5 years at the Clinical Hospital Center in Zagreb. Among 147 subjects, 108 were men (73.47%) and 39 women (26.53%). Distributions by age have a similar peak incidence of cutaneous ear tumors, around age 80, with distribution in the female population taking on a bimodal character with a secondary peak incidence around 45 years. Most respondents were diagnosed with BCC (43 patients), PCC (31 patients), actinic keratosis (28 patients), keloid (13 patients), naevus naevocellularis (9 patients) and seborrhoeic keratosis (8 patients). Cryotherapy was used to treat 35 patients, 14 of whom had a relapse after completing the cryotherapy approach (28.57%). Of the 112 patients treated by excision, recurrence of the disease was reported in 10 (8.20%). Although the incidence of recurrence after a surgical approach is lower, each patient requires an individualized and interdisciplinary approach (dermatological, otorhinolaryngological, and surgical) to provide him the best possible care.

• Keywords: kožni tumori uške; krioterapija; ekscizija
• Keywords (english): cutaneous tumors of the ear; cryotherapy; excision
• Language: croatian
• URN:NBN: urn:nbn:hr:105:357480
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-01-09 08:51:39