Utjecaj anemije na ishode hospitaliziranih COVID-19 bolesnika

master's thesis

• Title (english): Influence of anemia on outcomes of hospitalized COVID-19 patients
• Author: Zvonimir Kremer
• Mentor: Marko Lucijanić (mentor)
• Committee member: Vlatko Pejša (predsjednik povjerenstva)
• Committee member: Marija Bakula (član povjerenstva)
• Committee member: Marko Lucijanić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2022-09-20, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Covid-19 infektivna je bolest uzrokovana koronavirusom teškog akutnog respiratornog
sindroma 2 (SARS-CoV-2). U težim oblicima bolesti, ljudi starije životne dobi,
imunokompromitirani i pacijenti opterećeni komorbiditetima često zahtijevaju
hospitalizaciju. Anemija je stanje u kojemu krv ima smanjenu mogućnost prenošenja
kisika u tkiva te može utjecati na tijek liječenja i preživljenje pacijenata kod COVID-19
bolesti. Cilj ovog rada je istražiti povezanosti kliničkih ishoda liječenja s prisustvom
anemije prilikom hospitalizacije kod pacijenata zaraženih virusom SARS-Cov 2 u
tercijarnom centru KB Dubrava. Rađena je usporedba laboratorijskih, anamnestičkih i
demografskih parametara te broja komplikacija među grupama sa i bez anemije na
podatcima od 5872 pacijenata. Pacijenti s anemijom imali su značajne razlike u većini
mjerenih laboratorijskih parametara i veće opterećenje komorbiditetima. Prisutnost
anemije je bila povećana s većom vjerojatnosti pojave venske tromboembolije, velikog
krvarenja i smrti tijekom hospitalizacije. Anemija je značajan negativan prediktivni
čimbenik preživljenja pacijenata prilikom hospitalizacije zbog COVID-19 bolesti.

Abstract (english)

Covid-19 is an infectious disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). In more severe forms of the disease, elderly,
immunocompromised and patients with comorbidities often require hospitalization.
Anemia is a condition in which the blood has a reduced ability to transfer oxygen to the
tissues, and may affect the survival of patients with COVID-19 disease. The aim of this
paper is to investigate the relationship between clinical treatment outcomes and the
presence of anemia during hospitalization in patients infected with the SARS-Cov 2 virus
in the tertiary center of KB Dubrava. A comparison of laboratory, anamnestic and
demographic parameters and the number of complications between the groups with and
without anemia was made on the basis of data from 5872 patients. Patients with anemia
had significant differences in most of the measured laboratory parameters and a higher
burden of comorbidities. They had higher frequency of venous thromboembolism, major
bleeding and death during hospitalization. Anemia is a significant negative predictive
factor of patient survival during hospitalization due to COVID-19 disease.

• Keywords: anemija; SARS-CoV 2; hemoglobin; COVID-19
• Keywords (english): anemia; SARS-CoV 2; hemoglobin; COVID-19
• Language: croatian
• URN:NBN: urn:nbn:hr:105:082452
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-01-16 08:25:04