Izvedivost procjene gerastenije i sarkopenije u starijih hospitaliziranih bolesnika

master's thesis

• Title (english): Feasibility of assessing garestenia and sarcopenia in hospitalized elderly patients
• Author: Lana Palčić
• Mentor: Tajana Pavić (mentor)
• Committee member: Davor Hrabar (predsjednik povjerenstva)
• Committee member: Marija Bakula (član povjerenstva)
• Committee member: Tajana Pavić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2022-09-20, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Sa starenjem svjetske populacije budućnost donosi nove izazove u skrbi za stare osobe. Gerastenija i sarkopenija dva su vrlo važna gerijatrijska sindroma. Gerastenija označava s dobi povezano smanjenje fiziološke rezerve i reaktivnosti na unutarnje i vanjske stresore. Uključuje i socijalnu domenu, a ne samo fizičku. Budući da ne postoji jedinstvena definicija, za operacionalizaciju gerastenije koristimo se mjerama proizašlim iz različitih modela.
Sarkopenija je progresivni generalizirani poremećaj poprečno-prugastih mišića koji je povezan s povećanim rizikom od štetnih ishoda uključujući padove, prijelome, tjelesni invaliditet i smrt. Definirana je pomoću 3 parametra: smanjenjem mišićne snage, smanjenjem mišićne mase ili kvalitete, te smanjenom mišićnom funkcionalnošću.
Gerastenija i sarkopenija smatraju se stanjima koja nastupaju prije onesposobljenosti. Budući da se onesposobljenost smatra ireverzibilnom, prepoznavanje smanjene funkcionalnosti koja je zajednička sarkopeniji i gerasteniji predstavlja novu metu za intervencije.
No, da bi se moglo intervenirati, prvo se mora validirati alate za testiranje sarkopenije i gerastenije. Idući korak je uvođenje testova u svakodnevnu praksu. Studije izvedivosti ispituju koji su facilitirajući, a koji otežavajući faktori kod uvođenja tih testova.
Dosadašnja istraživanja podupiru uporabu SARC-F upitnika, mjerenje snage stiska šake, brzine hoda i mišićne mase u procjeni sarkopenije te uporabu Kliničke skale krhkosti, FRAIL i PRISMA-7 upitnika za procjenu gerastenije u bolničkim uvjetima.

Abstract (english)

As the world population ages, doctors are presented with new challenges in caring for the ever-increasing elderly population. Gerastenia and sarcopenia are two important geriatric syndromes. Gerastenia is a common geriatric syndrome characterized by age-associated decline in physiologic reserve and reactivity to external and internal stressors. It encompasses both the social and physical domain. As there is no consensus on the definition of gerastenia, this syndrome is operationalized in many ways. Sarcopenia is a progressive generalized dysfunction of the skeletal muscle associated with an increased risk of adverse health outcomes. It is defined by three parameters – muscle strength, muscle mass and/or quality, and physical performance. Gerastenia and sarcopenia are considered to be pre-disability states that share a common denominator – impaired physical function. As disability is considered to be irreversible, sarcopenia and gerastenia are potential targets for early intervention. For intervention to be possible, tools for recognising sarcopenia and gerastenia and grading the severity have to be developed and validated. The next step is translating tests into daily practice. Feasibility studies are used to assess the feasibility of performing these tests in different settings. Studies published in recent years support the use of the SARC-F questionnaire, gait speed and muscle mass to assess sarcopenia. The use of Clinical Frailty Scale, FRAIL and PRISMA-7 questionnaires is supported in the assesment of gerastenia.

• Keywords: gerastenija; sindrom krhkosti; sarkopenija; mjerenje
• Keywords (english): gerastenia; frailty syndrome; sarcopenia; measuring
• Language: croatian
• URN:NBN: urn:nbn:hr:105:263476
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-01-26 09:29:25