Pristup liječenju boli uzrokovane malignim tumorom

master's thesis

• Title (english): Approach to malignant tumor pain management
• Author: Ivor Pleić
• Mentor: Dinko Tonković (mentor)
• Committee member: Slobodan Mihaljević (predsjednik povjerenstva)
• Committee member: Jasmina Marić Brozić (član povjerenstva)
• Committee member: Dinko Tonković (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Cabinet for First Aid); Zagreb
• Defense date and country: 2022-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Anesthesiology and Reanimatology

Abstract

Maligne bolesti jedan su od najčešćih uzroka kroničnih morbiditeta kako u razvijenim zemljama, tako i u zemljama u razvoju. Ne čudi, stoga, kako je bol uzrokovana malignitetima važan javnozdravstveni izazov i učestao razlog nerijetko dramatičnog i dugotrajnog smanjenja kvalitete života zahvaćenih. Bol koja se javlja u pacijenata oboljelih od malignih tumora je multifaktorijalnog podrijetla, proizlazeći istovremeno iz samog patološkog djelovanja tumorskog tkiva, ali i kao reakcija na dijagnostičke postupke, kirurško liječenje i redovno primjenjivane citostatike i radioterapiju čije antineoplastično djelovanje uzrokuje oštećenje perifernih senzornih živaca. Spomenute karakteristike čine kontroliranje tumorske boli kompleksnim problemom s kojim se susreće većina pacijenata oboljelih od malignih tumora, ali i brojni liječnici i druge vokacije koji toj problematici pristupaju sa stručne strane. Znanstveno-stručnim napretkom u posljednjem stoljeću, a posebice u posljednjih nekoliko desetljeća, ostvareni su izvanredni pomaci u savladavanju tog problema primjenom novih pristupa i lijekova, ali i uvođenjem raznih komplementarnih i integrativnih metoda u suvremene terapijske planove.

Abstract (english)

Malignancies are one of the leading causes of chronic morbidity in developed countries, as well as in developing countries. It comes as no surprise that cancer pain is a major public health challenge and a frequent cause of an often dramatic and long-term decrease in life quality of the affected. The origin of the pain found in cancer patients is multifactorial, arising concurrently from the pathological effect of the tumor tissue itself, but also as a reaction to diagnostic procedures, surgical treatment, and commonly used cytostatic agents and radiotherapy whose antineoplastic action damages peripheral sensory nerves. The mentioned characteristics make tumor pain management a complex problem encountered by most patients afflicted by malignancies, but also various medical doctors and other experts who approach the problematics from a professional aspect. Owing to scientific and professional progress during the last century, and especially in the last few decades, remarkable steps have been realized in overcoming the issue by implementing novel approaches and drugs, and also introducing various complementary and integrative methods in current therapeutic plans.

• Keywords: maligni tumori; liječenje boli
• Keywords (english): malignancies; pain management
• Language: croatian
• URN:NBN: urn:nbn:hr:105:507847
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-02-06 12:43:55