Korelacija između pozitivnog brisa rodnice i međice rodilja na beta hemolitički streptokok grupe B i sepse novorođenčadi

master's thesis

• Title (english): Correlation between positive vaginal and perineum swab on beta haemolytic streptococcus group B and newborn sepsis
• Author: Renee Širac
• Mentor: Vladimir Blagaić (mentor)
• Committee member: Tatjana Pavelić Turudić (predsjednik povjerenstva)
• Committee member: Dinka Pavičić Baldani (član povjerenstva)
• Committee member: Vladimir Blagaić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Gynecology and Obstetrics); Zagreb
• Defense date and country: 2022-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics

Abstract

Cilj ovog rada je procijeniti korelaciju između pozitivnog brisa rodnice i međice rodilja na beta hemolitički streptokok grupe B i sepse novorođenčadi te procijeniti učestalost kolonizacije rodilja beta hemolitičkim streptokokom grupe B u populaciji trudnica na području Grada Zagreba i okolice.
U razdoblju od studenog 2020. do srpnja 2021. na Odjelu za porodništvo i ginekologiju Kliničke bolnice ,,Sveti Duh” proučavano je ukupno 2,073 žena, a rezultati su prikupljeni iz bolničkog informacijskog sustava. Podaci za razdoblje od 2016. do 2021. godine uzeti su retrospektivno i uspoređeni s dobivenim rezultatima.
Prevalencija majčinske kolonizacije beta hemolitičkim streptokokom grupe B iznosi 7.4% u pacijentica koje su sudjelovale u programu probira i 5.8% u ukupnoj populaciji od 2,073 pacijentica. Za vrijeme istraživanja i šestogodišnjeg razdoblja zabilježeno je nula slučajeva novorođenačke sepse. Za šestogodišnje razdoblje zabilježene su 4 anafilaktičke reakcije, ali u razdoblju od studenog do srpnja nije zabilježena niti jedna anafilaktička reakcija.
Prevalencija BHSB pozitivnih rodilja u ovoj studiji značajno je niža, nego procjena za globalnu i hrvatsku populaciju. Pozitivan bris rodnice i međice nije doveden u korelaciju sa sepsom novorođenčadi zbog djelotvornosti profilakse.

Abstract (english)

The aim of this paper is to assess the correlation between positive vaginal and perineal swab on Group B Streptococcus and sepsis in newborns; to assess the prevalence of maternal GBS colonization in the population of pregnant women in the City of Zagreb and Zagreb area.
A total of 2,073 women was studied between November 2020 and July 2021 at the Department of Obstetrics and Gynecology, Clinical Hospital “Holy Spirit " and results were collected from the hospital information system. Data for the 2016-2021 period were taken retrospectively and compared to obtained results.
The prevalence of maternal GBS colonization is 7.4% in the patients who had taken the screening program and 5.8% among the total population of 2,073 patients. Zero cases of newborn sepsis were reported for the time of the study and the six-year period. For the six-year period, 4 anaphylactic reactions were recorded, on the other hand for the period of November 2020 and July 2021 none of anaphylactic reaction was recorded.
The prevalence of GBS-positive mothers in this study is significantly lower than global average and official Croatian prevalence. Positive vaginal and perineal swabs were not correlated to sepsis in newborns due to the effectiveness of prophylactics.

• Keywords: beta hemolitički streptokok grupe B; prevalencija; sepsa; novorođenčad
• Keywords (english): beta haemolythic streptococcus group B; prevalence; sepsis; newborns
• Language: croatian
• URN:NBN: urn:nbn:hr:105:248570
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-02-28 10:16:20