INDIKACIJE I KIRURŠKA TEHNIKA UGRADNJE POTPUNOG UMJETNOG SRCA

master's thesis

• Title (english): INDICATIONS AND SURGICAL TECHNIQUE OF IMPLANTING TOTAL ARTIFICIAL HEART
• Author: Juraj Knezović
• Mentor: Bojan Biočina (mentor)
• Committee member: Davor Miličić
• Committee member: Tomislav Meštrović
• Committee member: Bojan Biočina
• Granter: University of Zagreb; School of Medicine; (Department of Surgery); Zagreb
• Defense date and country: 2015-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Surgery

Abstract

Srce je najvažniji mišić u ljudskom tijelu. Svojim radom osigurava dotok krvi do svih dijelova tijela. Bolesti srca i krvnih žila su najzastupljenije u svijetu, u razvijenim zemljama dosežu 50 % mortaliteta. Velik broj ovih bolesti vodi do zatajivanja srca. Do nekog stupnja bolest se može liječiti medikametozno, nakon toga rješenje je transplantacija. No, broj donorskih organa je daleko manji od stvarnih potreba bolesnika, a i svi bolesnici nisu kandidati za transplantaciju. Zato je 1964.... More godine u Americi pokrenuta inicijativa za ugradnju potpunog umjetnog srca (engl. total artifical heart-TAH), a prvo potpuno umjetno srce je ugrađeno 1969. godine. Danas se koriste dva tipa TAH: „SynCardia“ i „AbioCor“. Glavna razlika između ova dva uređaja je ta što je „SynCardia“ spojen na vanjski izvor napajanja, dok „AbioCor“ nije. „SynCardia“ ima cijevi koje kroz otvore na prednjoj trbušnoj stijenci, izlaze iz tijela na vanjski izvor energije. „AbioCor“ je potpuno sadržan u tijelu. Indikacije za ugradnju potpunog umjetnog srca su zadnja faza biventrikularnog zatajivanja srca (koja može biti uzrokovana kardiomiopatijama, kardiogenim šokom, masivnim infarktom srca, kongenitalnim srčanim greškama kod odraslih, amiloidozom), reakcija odbacivanja presatka, pacijenti kojima je nužna transplantacija. Kirurška tehnika ugradnje TAH je vrlo složena i izvodi se u sedam koraka: sternotomija i kirurški pristup, uklanjanje srca, pripreme za anastomozu, anastomoza, postavljenje klijetki i zatvaranje prsnog koša. Komplikacije operacije su krvni ugrušci, krvarenje, infekcije i kvarovi uređaja. Less

Abstract (english)

Heart is the most importanat muscle in human body. Its work ensures the flow of blood to all parts of the body. Heart and cardiovascular diseases are ithe most prevalent worldwide causing up to 50 % mortality in developed countries. Large number of heart diseases lead to heart failure. Some degrees of heart failure can be treated with medication, while other require heart transplantation. However, the number of donor organs is far lower than the real needs of patients, and all patients... More are not candidates for transplantation. Therefore, an initiative for implanting the total artificial heart (TAH) was started in USA, and first implantation was preformed in 1969. Today there are two types of TAH in use, " SynCardia" and "AbioCor". The main difference between these two devices is that "SynCardia" is connected to an external power source, while "AbioCor" is not. "SynCardia" has tubes running through holes in the anterior abdominal wall, leaving the body to an external power source. "AbioCor" is completely contained in the chest. Indications for TAH are last phase biventricular heart failure (which can be caused by: cardiomyopathies, cardiogenic shock, a massive heart attack, congenital heart defects in adults, amyloidosis), graft rejection, patients who need transplantation. Implantation of TAH is a challenging surgical procedure. It is performed in seven steps: sternotomy and surgical access, removal of the heart, preparation of anastomoses, anastomoses, the appointment of the ventricles and the closure of the chest. Complications of surgery are blood clots, bleeding, infection and device failures. Less

• Keywords: potpuno umjetno srce; indikacije; zatajivanje srca; kirurška tehnika ugradnje
• Keywords (english): total artificial heart; indications; heart failure; surgical technique
• Language: croatian
• URN:NBN: urn:nbn:hr:105:877311
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-04-04 09:25:08