Ekvivalent: Sindrom suhog oka povezan s nošenjem maski za lice tijekom pandemije izazvane COVID-19 virusom – kako maska za lice utječe za simptome sindroma suhog oka

professional thesis

• Title (english): Equivalent: Mask-Associated Dry Eye During COVID-19 Pandemic–How Face Masks Contribute to Dry Eye Disease Symptoms
• Author: Matija Blažeka
• Mentor: Ivanka Petric Vicković (mentor)
• Mentor: Miro Kalauz (mentor)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2023-03-22, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Ophthalmology

Abstract

Cilj ovog prospektivnog kohortnog istraživanja bio je utvrditi uzrokuje li nošenje maski za lice pojavu ili pogoršanje simptoma suhog oka. Uključeno je 203 ispitanika koji su svi nosili maske za lice radi regulacija vezanih uz Covid-19 pandemiju. Ispunili su modificirani OSDI upitnik te su podijeljeni u grupe po spolu, godinama, vremenu nošenja maske za lice te prethodnom postojanju simptoma suhog oka. Rezultati su pokazali da postoji statistički značajna razlika u višim vrijednostima OSDI upitnika kod žena u odnosu na muškarce te da je grupa koja je nosila maske za lice u trajanju od 3-6 sati na dan imala statistički značajno više vrijednosti OSDI upitnika nego grupa koja je nosila masku za lice manje od 3 sata na dan. Ovo istraživanje potvrdilo je postojanje sindroma suhog oka povezanog s nošenjem maski za lice i to značajnije kod žena, ispitanika s prijašnjim simptomima suhog oka te nošenjem maski za lice duže od 3 sata na dan. Na temelju toga oftalmolozi mogu savjetovati svoje pacijente o potencijalnim rizicima uslijed neadekvatnog nošenja maski za lice.

Abstract (english)

Background: In the year 2020 we observe the world adapting to „new normal“ due to the COVID-19 pandemic, ways of which include physical distancing, hand hygiene, and wearing a face mask. There is no conclusive evidence about ocular manifestations of the new coronavirus infection, but cases of conjunctivitis, keratitis, and episcleritis have been reported
in infected individuals.
Objective: Determining if wearing a face mask during COVID-19 pandemic causes a new onset or deterioration of previously existing dry eye disease (DED).
Methods: A prospective cohort study included 203 participants, all using surgical facemasks daily due to new regulations during COVID-19 pandemic. Participants completed a survey, containing modified Ocular Surface Disease Index (OSDI) questionnaire. They were divided into groups according to: sex, age, duration of face mask-wear, and existence of prior DED history.
Results: Our results indicate that women have a statistically higher OSDI score compared to men (14.4 (IQR = 2.4 – 41.7) vs. 5.0 (IQR = 0.0 – 24.4); P = .004). Age did not significantly affect OSDI median values. Group that used masks from 3 to 6 hours/ day demonstrated significantly higher OSDI scores compared to <3 hour/day group (15.3 (IQR = 8.3 – 47.7) vs. 8.3 (IQR = 0.0 – 35.1); P = .001). OSDI score was significantly greater in participants with prior DED history compared to those without it (36.1 (IQR = 14.1 – 61.6) vs. 4.2 (IQR = 2.3 – 8.3); P <.001). Participants with prior DED exhibited greater worsening of their disturbances during mask wearing period compared to the ones without previous DED (54.8% vs. 17.7%, Chi-Square 28.3 DF1; P <.001), regardless of daily mask wear duration.
Conclusion: Our study confirmed the existence of mask-associated dry eye (MADE), most profoundly in females, subjects with a history of prior DED, and if wearing a face mask lasts longer than 3 hours per day. Ophthalmologists should advise their patients of the potential ocular surface health risks related to inadequately fitted facemasks.

• Keywords: Suho oko; maska za lice; koronavirus; COVID-19; MADE; površina oka
• Keywords (english): Dry eye; Face mask; Coronavirus; COVID-19; MADE; Ocular surface
• Language: croatian
• URN:NBN: urn:nbn:hr:105:655993
• Study programme: Title: Ophthalmology and optometry; Study programme type: university; Study level: postgraduate specialist; Academic / professional title: sveučilišni/a magistar/magistra oftalmolgije i optometrije (sveučilišni/a magistar/magistra oftalmolgije i optometrije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-01-26 09:41:44