Ekvivalent: Vrijednosti prostata specifičnog antigena (PSA) u bolesnika s adenokarcinomom prostate niskog i visokog rizika

professional thesis

• Title (english): Equivalent: Prostate-specific antigen (PSA) values in patients with low-and high-risk prostatic adenocarcinoma
• Author: Silvija Mašić
• Mentor: Božo Krušlin (mentor)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2024-01-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Basic Medical Sciences; Cytology, Histology and Embryology

Abstract

Prostatic adenocarcinoma (PC) comprises around 19% of malignancies in Croa-tian male population. On the basis of PSA value,Gleason score, grading group and clinical stage, PC can be classified into low- and high-risk groups which is significant for different therapeutic regimens and prognostic outcomes.In this retrospective study, we analyzed the difference in preoperative PSA value in a group of 272 patients who underwent radical prostatectomy and were diagnosed with PC adenocarcinoma in our institution in a period from January 1st,2018 untill December 31st,2018.Subsequently, they were divided into low- and high- risk prostatic adenocarcinoma groups. Our results demonstrated positive correlation in preoperative PSA values between the groups and therefore support the use of PSA as one of the parameters in defining low- and high-risk prostatic adenocarcinoma categories.

Abstract (croatian)

Adenokarcinom prostate čini oko 19% maligniteta u muškoj populaciji Hrvata. Svi dijagnosticirani adenokarcinomi prostate se s obzirom na vrijednost PSA, Gleason zbroj i klinički stadij mogu svrstati u skupine niskog i visokog rizika. U ovoj retrospektivnoj studiji analizirali smo razliku u vrijednostima preoperativnog PSA u skupini od 272 pacijenta kojima je dijagnosticiran adenokarcinom prostate nakon radikalne prostatektomije učinjene u našoj ustanovi u razdoblju od jedne godine (01. siječnja do 31. prosinca 2018.), a koji su podijeljeni u skupine adenokarcinoma prostate niskog i visokog rizika. Rezultati naše studije pokazuju pozitivnu korelaciju u vrijednostima preoperativnog PSA između grupa. Nadalje, rezultati naše analize podupiru upotrebu PSA kao jednog od parametara u definiranju kategorija niskog i visokog rizika karcinoma prostate.

• Keywords: Prostatic Adenocarcinoma; PSA; Gleason Grade; Low-risk; High-risk
• Keywords (croatian): PSA; Gleason zbroj; adenokarcinom prostate visokog rizika
• Language: english
• URN:NBN: urn:nbn:hr:105:183858
• Study programme: Title: Pathology and cytology; Study programme type: university; Study level: postgraduate specialist; Academic / professional title: sveučilišni/a magistar/magistra patologije i citologije (sveučilišni/a magistar/magistra patologije i citologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-02-16 08:56:11