prikaz prve stranice dokumenta The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients
  Download
PDF 89.98 KB
Scientific paper - Original scientific paper
The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients
Collegium Antropologicum, 35 (2011), 1; 93-101. urn:nbn:hr:105:740190
Galić, Gordan; Tomić, Monika; Galešić, Krešimir; Kvesić, Ante; Šoljić, Martina; Lončar, Zdravka; Valenčić, Maksim; Martinović, Željko; Vučkov, Šime

Cite this document

Galić, G., Tomić, M., Galešić, K., Kvesić, A., Šoljić, M., Lončar, Z. ... Vučkov, Š. (2011). The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients . Collegium Antropologicum, 35. (1), 93-101. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:740190

Galić, Gordan, et al. "The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients ." Collegium Antropologicum, vol. 35, no. 1, 2011, pp. 93-101. https://urn.nsk.hr/urn:nbn:hr:105:740190

Galić, Gordan, Monika Tomić, Krešimir Galešić, Ante Kvesić, Martina Šoljić, Zdravka Lončar, Maksim Valenčić, Željko Martinović and Šime Vučkov. "The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients ." Collegium Antropologicum 35, no. 1 (2011): 93-101. https://urn.nsk.hr/urn:nbn:hr:105:740190

Galić, G., et al. (2011) 'The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients ', Collegium Antropologicum, 35(1), pp. 93-101. Available at: https://urn.nsk.hr/urn:nbn:hr:105:740190 (Accessed 21 December 2024)

Galić G, Tomić M, Galešić K, Kvesić A, Šoljić M, Lončar Z, and sur.. The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients . Collegium Antropologicum [Internet]. 2011 March [cited 2024 December 21];35(1):93-101. Available at: https://urn.nsk.hr/urn:nbn:hr:105:740190

G. Galić, et al., "The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients ", Collegium Antropologicum, vol. 35, no. 1, pp. 93-101, March 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:740190. [Accessed: 21 December 2024]

Please login to the repository to save this object to your list.
Metadata
Title (english)The etiological relation between serum iron level and infection incidence in hemodialysis uremic patients
Title (croatian)Etiološi odnos serumske razine željeza i incidencije infekcije u bolesnika liječenih kroničnom hemodijalizom
AuthorGordan Galić
AuthorMonika Tomić
AuthorKrešimir Galešić
AuthorAnte Kvesić
AuthorMartina Šoljić
AuthorZdravka Lončar
AuthorMaksim Valenčić
AuthorŽeljko Martinović
AuthorŠime Vučkov
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Through the treatment of anaemia in dialysis patients part of the iron ions remain free in the serum which is at the bacterias disposal for growth and the strengthening of their virulence. The linear relation of the increased serum iron level and tissue iron stores in the body and the infection incidence in dialysed patients has become more emphasised. The need of a clearly defined upper threshold of the serum iron concentration limit has been mentioned in scientific journals intensely, and consequently the demand for more precise professional instructions for anaemia treatment. For the purpose of participating in these professional and scientific discussions, we have observed the relation between the iron overload of the organism and complication incidence in 120 of our haemodialysis uremic patients, with special emphasis on infections. It has been established that the sepses incidence is much higher in patients with a serum ferritin concentration above 500 microg/L, than in those patients with a ferritin level lower than the mentioned value (Chi2 = 7.857, p = 0.005). The incidence of vascular access infection is significantly higher in those patients with a serum ferritin level above 500 microg/L than in those patients with a ferritin level lower than the mentioned value (Chi2 = 23.186, p = 0.001). Furthermore, it has been determined that the incidence of total infection in patients is 3.8 episodes per 100 patients months, which is in accordance to the referral values of other authors. CONCLUSION--In the analysis of the achieved results, it has been determined that the infection incidence is significantly higher in dialysed patients with a serum iron level higher than 500 microg/L, than in those patients with lower values.
Abstract (croatian)
Tijekom liječenja anemije u dijaliziranih bolesnika dio jona željeza ostaje u serumu slobodan tako da je na raspolaganju bakterijama za rast i jačanje njihove virulencije. Sve se više ukazuje u dijaliziranih bolesnika na linearni odnos povišene razine željeza u serumu i tkivnim depoima s jedne i incidencije upale s druge strane. U stručnom se tisku sve glasnije ukazuje na potrebu jasnog određivanja gornjeg praga limita serumske koncentracije željeza, a dosljedno tome i na određivanje preciznijih stručnih uputa za liječenje anemije. U nakani da se uključimo u te stručne i znanstvene rasprave promatrali smo u 120 naših bolesnika liječenih kroničnom hemodijalizom odnos opterećenosti organizma željezom i incidencije komplikacija, a posebno infekcije. Utvrđeno je da je incidencija sepse značajno viša u ispitanika sa serumskom razinom feritina iznad 500 microg/L, nego u onih s razinom feritina nižom od navedene vrijednosti (χ2=7,857, p=0,005). Incidencija infekcije vaskularnog pristupa isto je tako značajno viša u ispitanika sa serumskom razinom feritina iznad 500 microg/L, nego u onih s razinom feritina nižom od navedene vrijednosti (χ2=23,186, p=0,001). Incidencija sveukupne infekcije u svih ispitanika iznosi 3,8 epizoda na 100 bolesnikovih mjeseci i kreće se unutar referiranih vrijednosti drugih autora. Zaključak – Raščlambom postignutih rezultata utvrđeno je da je incidencija infekcije značajno veća u dijaliziranih bolesnika sa serumskom razinom feritina višom od 500 microg/L, nego u onih s nižim vrijednostima.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 35, no. 1, pp. 93-101
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:740190
Publication2011-03
Document URLhttps://hrcak.srce.hr/64749
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:04:29