Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates

Kaštelan, Darko; Vlak, Tonko; Lozo, Petar; Gradišer, Marina; Mijić, Šime; Nikolić, Tatjana; Miškić, Blaženka; Car, Dolores; Tajsić, Gordana; Dušek, Tina; Jajić, Zrinka; Grubišić, Frane; Poljičanin, Tamara; Bakula, Miro; Džubur, Fedja; Strižak-Ujević, Matilda; Kadojić, Mira; Radman, Maja; Vugrinec, Maja; Kušter, Željka; Pekez, Marijeta; Radović, Endi; Labar, Ljubica; Crnčević-Orlić, Željka; Koršić, Mirko

doi:10.3109/07435800.2010.505218

prikaz prve stranice dokumenta Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates

Scientific paper - Original scientific paper

Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates

Endocrine Research, 35 (2010), 4; 165-173. https://doi.org/10.3109/07435800.2010.505218

Kaštelan, Darko; Vlak, Tonko; Lozo, Petar; Gradišer, Marina; Mijić, Šime; Nikolić, Tatjana; Miškić, Blaženka; Car, Dolores; Tajsić, Gordana; Dušek, Tina; Jajić, Zrinka; Grubišić, Frane; Poljičanin, Tamara; Bakula, Miro; Džubur, Fedja; Strižak-Ujević, Matilda; Kadojić, Mira; Radman, Maja; Vugrinec, Maja; Kušter, Željka; Pekez, Marijeta; Radović, Endi; Labar, Ljubica; Crnčević-Orlić, Željka; Koršić, Mirko More authors...

Cite this document

APA 6th Edition

Kaštelan, D., Vlak, T., Lozo, P., Gradišer, M., Mijić, Š., Nikolić, T. ... Koršić, M. (2010). Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates. Endocrine Research, 35. (4), 165-173. doi: 10.3109/07435800.2010.505218

MLA 8th Edition

Kaštelan, Darko, et al. "Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates." Endocrine Research, vol. 35, no. 4, 2010, pp. 165-173. https://doi.org/10.3109/07435800.2010.505218

Chicago 17th Edition

Kaštelan, Darko, Tonko Vlak, Petar Lozo, Marina Gradišer, Šime Mijić, Tatjana Nikolić, Blaženka Miškić, et al. "Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates." Endocrine Research 35, no. 4 (2010): 165-173. https://doi.org/10.3109/07435800.2010.505218

Harvard

Kaštelan, D., et al. (2010) 'Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates', Endocrine Research, 35(4), pp. 165-173. doi: 10.3109/07435800.2010.505218

Vancouver

Kaštelan D, Vlak T, Lozo P, Gradišer M, Mijić Š, Nikolić T, and sur.. Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates. Endocrine Research [Internet]. 2010 [cited 2024 December 19];35(4):165-173. doi: 10.3109/07435800.2010.505218

IEEE

D. Kaštelan, et al., "Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates", Endocrine Research, vol. 35, no. 4, pp. 165-173, 2010. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:106965. [Accessed: 19 December 2024]

Cite this item: https://urn.nsk.hr/urn:nbn:hr:105:106965

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Metadata

Title (english)	Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates
Author	Darko Kaštelan
Author	Tonko Vlak
Author	Petar Lozo
Author	Marina Gradišer
Author	Šime Mijić
Author	Tatjana Nikolić
Author	Blaženka Miškić
Author	Dolores Car
Author	Gordana Tajsić
Author	Tina Dušek
Author	Zrinka Jajić
Author	Frane Grubišić
Author	Tamara Poljičanin
Author	Miro Bakula
Author	Fedja Džubur
Author	Matilda Strižak-Ujević
Author	Mira Kadojić
Author	Maja Radman
Author	Maja Vugrinec
Author	Željka Kušter
Author	Marijeta Pekez
Author	Endi Radović
Author	Ljubica Labar
Author	Željka Crnčević-Orlić
Author	Mirko Koršić
Author's institution	University of Zagreb School of Medicine
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences
Abstract (english)	OBJECTIVE: The present study was designed to assess the effect of monthly ibandronate on health-related quality of life (HR-QoL) in patients with postmenopausal osteoporosis previously treated with weekly bisphosphonates. ----- METHODS: HR-QoL was assessed by Euroqol (EQ-5D) and Osteoporosis Targeted Quality of Life (OPTQoL) questionnaires. ----- RESULTS: The EQ-5D questionnaire showed significant improvement associated with ibandronate treatment, occurring in mobility (p < 0.01), usual activity (p < 0.01), pain/discomfort (p < 0.05), and anxiety/depression (p < 0.05). In addition, ibandronate treatment considerably improved patients' perceived health on a visual analog scale (p < 0.001). For the OPTQoL questionnaire, patients reported less physical difficulty (p < 0.001), fewer adaptations in their lives (p < 0.001), and less fear (p < 0.001) with ibandronate than with weekly bisphosphonates. ----- CONCLUSION: The study demonstrated that patients who were transferred from weekly bisphosphonates to a monthly ibandronate experienced improved HR-QoL.
Keywords (english)
Language	english
Publication type	Scientific paper - Original scientific paper
Publication status	Published
Peer review	Peer review
Publication version	Accepted version
Journal title	Endocrine Research
Numbering	vol. 35, no. 4, pp. 165-173
p-ISSN	0743-5800
DOI	https://doi.org/10.3109/07435800.2010.505218
URN:NBN	urn:nbn:hr:105:106965
Publication	2010
Document URL	https://doi.org/10.3109/07435800.2010.505218
Type of resource	Text
Access conditions	Open access
Terms of use
Created on	2024-03-27 19:10:37