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Scientific paper - Original scientific paper
A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease
Journal of the Neurological Sciences, 248 (2006), 1-2; 251-254. https://doi.org/10.1016/j.jns.2006.05.027
Relja, Maja; Klepac, Nataša

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Relja, M. & Klepac, N. (2006). A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease. Journal of the Neurological Sciences, 248. (1-2), 251-254. doi: 10.1016/j.jns.2006.05.027

Relja, Maja and Nataša Klepac. "A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease." Journal of the Neurological Sciences, vol. 248, no. 1-2, 2006, pp. 251-254. https://doi.org/10.1016/j.jns.2006.05.027

Relja, Maja and Nataša Klepac. "A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease." Journal of the Neurological Sciences 248, no. 1-2 (2006): 251-254. https://doi.org/10.1016/j.jns.2006.05.027

Relja, M. and Klepac, N. (2006) 'A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease', Journal of the Neurological Sciences, 248(1-2), pp. 251-254. doi: 10.1016/j.jns.2006.05.027

Relja M, Klepac N. A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease. Journal of the Neurological Sciences [Internet]. 2006 October 25 [cited 2024 November 29];248(1-2):251-254. doi: 10.1016/j.jns.2006.05.027

M. Relja and N. Klepac, "A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease", Journal of the Neurological Sciences, vol. 248, no. 1-2, pp. 251-254, October 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:928422. [Accessed: 29 November 2024]

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Metadata
Title (english)A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease
AuthorMaja Relja
AuthorNataša Klepac
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The cognitive performance of 55 non-demented idiopathic Parkinson's disease (PD) patients treated with levodopa alone or receiving dopamine agonist pramipexole as add-on therapy to levodopa was evaluated in the present study during 6 months of treatment. Neuropsychological tests were administered two times. In the first assessment to differentiate test sensitive to cognitive changes typical for PD control group was also assessed. After 6 months of treatment PD patients were retested only with tests that differentiate them from control group. Compared to controls PD patients showed inferior performance on Stroop Interference test, Trail Making test, letter fluency and Hooper Visual Organization Test. No statistically significant differences between two groups and first and second neuropsychological assessment were found. Present findings indicate that pramipexole as add-on therapy to levodopa is safe in non-demented PD patients in terms of the effect on cognitive performance.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleJournal of the Neurological Sciences
Numberingvol. 248, no. 1-2, pp. 251-254
p-ISSN0022-510X
DOIhttps://doi.org/10.1016/j.jns.2006.05.027
URN:NBNurn:nbn:hr:105:928422
Publication2006-10-25
Document URLhttps://doi.org/10.1016/j.jns.2006.05.027
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:21:46