Trends in lung cancer incidence and mortality in Croatia, 1988-2008

Scientific paper - Original scientific paper

• Author: Mateja Janković
• Author: Miroslav Samaržija
• Author: Marko Jakopović
• Author: Tomislav Kuliš
• Author: Ariana Znaor
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

AIM:

To describe and interpret lung cancer incidence and mortality trends in Croatia between 1988 and 2008. ----- METHODS:

Incidence data on lung cancer for the period 1988-2008 were obtained from the Croatian National Cancer Registry, while mortality data were obtained from the World Health Organization mortality database. Population estimates for Croatia were obtained from the Population Division of the Department of Economic and Social Affairs of the United Nations. We also calculated and analyzed age-standardized incidence and mortality rates. To describe time incidence and mortality trends, we used joinpoint regression analysis. ----- RESULTS:

Lung cancer incidence and mortality rates in men decreased significantly in all age groups younger than 70 years. Age-standardized incidence rates in men decreased significantly by -1.3% annually. Joinpoint analysis of mortality in men identified three trends, and average annual percent change (AAPC) decreased significantly by -1.1%. Lung cancer incidence and mortality rates in women increased significantly in all age groups older than 40 years and decreased in younger women (30-39- years). Age-standardized incidence rates increased significantly by 1.7% annually. Joinpoint analysis of age-standardized mortality rates in women identified two trends, and AAPC increased significantly by 1.9%. ----- CONCLUSION:

Despite the overall decreasing trend, Croatia is still among the European countries with the highest male lung cancer incidence and mortality. Although the incidence trend in women is increasing, their age standardized incidence rates are still 5-fold lower than in men. These trends follow the observed decrease and increase in the prevalence of male and female smokers, respectively. These findings indicate the need for further introduction of smoking prevention and cessation policies targeting younger population, particularly women.

Abstract (croatian)

Trendovi incidencije i mortaliteta od raka pluća u Hrvatskoj, 1988. do 2008. ----- Cilj Opisati i interpretirati trendove incidencije i mortaliteta od raka pluća u Hrvatskoj između 1988. i 2008. ----- Postupci Podaci o incidenciji prikupljeni su iz Hrvatskog registra za rak, dok su podaci o mortalitetu prikupljeni iz baze podataka o mortalitetu Svjetske zdravstvene organizacije. Korištene su populacijske procjene za Hrvatsku Populacijskog odsjeka Odjela za ekonomska i socijalna pitanja Ujedinjenih naroda. Izračunali smo i analizirali stope incidencije i mortaliteta standardizirane po dobi. Da bismo opisali trendove incidencije i mortaliteta, koristili smo regresijsku analizu uz pomoć točaka spajanja (engl, joinpoint regression analysis). ----- Rezultati Stope incidencije i mortaliteta kod muškarca značajno su se smanjile u svim dobnim skupinama mlađim od 70 godina. Stope incidencije standardizirane po dobi značajno su se smanjivale za -1,3% godišnje. Analiza mortaliteta uz pomoć točaka spajanja kod muškaraca pokazala je tri trenda, a prosječni godišnji postotak promjene (engl, AAPC) pokazao je značajan pad od -1,1% godišnje. Stope incidencije i mortaliteta od raka pluća kod žena značajno su porasle u svim dobnim skupinama starijim od 40 godina, a smanjile se kod mlađih žena (30-39 godina). Stope incidencije standardizirane po dobi značajno su rasle za 1,7% godišnje. Analiza stopa mortaliteta standardiziranih po dobi uz pomoć točaka spajanja kod žena pokazala je 2 trenda, a AAPC je značajno porastao (1,9% godišnje). ----- Zaključak Usprkos ukupnom trendu smanjenja, Hrvatska je još uvijek među europskim zemljama s najvećim mortalitetom od raka pluća kod muškaraca. Iako trend incidencije kod žena raste, stope incidencije standardizirane po dobi su još uvijek 5 puta niže nego kod muškaraca. Ovi rezultati prate smanjenje prevalencije pušenja kod muškaraca odnosno porast kod žena. Naše istraživanje ukazuje na potrebu za daljnjim uvođenjem mjera za prestanak i prevenciju pušenja kod mlađe populacije, pogotovo žena.

• Keywords (english): Adult; Aged; Aged, 80 and over; Croatia/epidemiology; Female; Humans; Incidence; Lung Neoplasms/epidemiology; Male; Middle Aged; Registries; Retrospective Studies
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Croatian Medical Journal
• Numbering: vol. 53, no. 2, pp. 93-99
• p-ISSN: 0353-9504
• DOI: https://doi.org/10.3325/cmj.2012.53.93
• URN:NBN: urn:nbn:hr:105:487395
• Publication: 2012-04
• Document URL: http://www.cmj.hr/2012/53/2/22522986.htm
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-27 19:34:19