Comparative study of antibacterial and antifungal effects of rigid gas permeable contact lens disinfecting solutions

Scientific paper - Original scientific paper

• Title (croatian): Komparativna studija antibakterijskih i antigljivičnih svojstava tekućina za dezinfekciju polutvrdih kontaktnih leća
• Author: Tomislav Kuzman
• Author: Marija Barišić Kutija
• Author: Rajko Kordić
• Author: Smiljka Popović-Suić
• Author: Sonja Jandroković
• Author: Ivan Škegro
• Author: Rajko Pokupec
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

The aim of this study was to compare antimicrobial efficacy of rigid contact lens disinfecting solutions. We tested five commercially available solutions: Unique pH (Alcon Laboratories), Boston Advance (Polymer Technology Corp.), Nitilens Conditioner GP (Avizor), Total Care (AMO), Boston Simplus (Bausch&Lomb). Their efficacy to disinfect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) and Staphylococcus epidermidis (isolated from our laboratory) was tested. All tested solutions reduced concentrations of bacteria and fungi below 1000 CFU/mL (Colony forming unit; reduction by 3 log and 1 log, respectively) after the 8 hours period. Overall, all contact lens care solutions showed good disinfecting activity against tested bacteria and fungi, with more variation in their antifungal than in antibacterial efficacy. Results of our study might be valuable when selecting appropriate solutions for non-compliant contact lens wearers.

Abstract (croatian)

Cilj našeg istraživanja je bila usporedba antibakterijskih i antigljivičnih svojstava pet tekućina za dezinfekciju polutvrdih
kontaktnih leća. Testirali smo sljedeće tekućine: Unique pH (Alcon Laboratories), Boston Advance (Polymer
Technology Corp.), Nitilens Conditioner GP (Avizor), Total Care (Advanced Medical Optics), Boston Simplus (Bausch
& Lomb). Testirali smo njihovu efikasnost u dezinfekciji fiziološke otopine kontaminirane sljedećim sojevima mikroorganizama
American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC
25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) i Staphylococcus epidermidis (soj
izoliran iz našeg laboratorija). Sve testirane tekućine smanjile su koncentraciju bakterija i gljivica ispod 1000 CFU/mL
(Colony forming unit; smanjenje 3 log i 1 log od početne koncentracije) nakon 8-satnog dezinfekcijskog razdoblja. Međutim, postoje razlike u njihovoj dezinfekcijskoj učinkovitosti. Rezultati naše studije pokazuju kako sve testirane tekućine imaju dobar dezinfekcijski učinak protiv testiranih bakterija i gljivica, pokazujući nešto veće međusobne razlike
antigljivične nego antibakterijske učinkovitosti. Uočene razlike učinkovitosti tekućina za dezinfekciju leća mogle bi
doći do izražaja kod nesuradljivih nositelja kontaktnih leća, te bi rezultati ovog istraživanja mogli biti značajni kod
odabira adekvatne tekućine za nesuradljive pacijente.

• Keywords (english): Anti-Bacterial Agents/pharmacology; Antifungal Agents/pharmacology; Contact Lens Solutions/pharmacology; Contact Lenses
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 37, no. S. 1, pp. 127-131
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:060476
• Publication: 2013-04
• Document URL: https://hrcak.srce.hr/102861
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-27 19:55:01