prikaz prve stranice dokumenta Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma
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Scientific paper - Original scientific paper
Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma
Cancer Letters, 238 (2006), 2; 224-229. https://doi.org/10.1016/j.canlet.2005.07.003
Grbeša, Ivana; Ivkić, Mirko; Pegan, Boris; Gall-Trošelj, Koraljka

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Grbeša, I., Ivkić, M., Pegan, B. & Gall Trošelj, K. (2006). Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma. Cancer Letters, 238. (2), 224-229. doi: 10.1016/j.canlet.2005.07.003

Grbeša, Ivana, et al. "Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma." Cancer Letters, vol. 238, no. 2, 2006, pp. 224-229. https://doi.org/10.1016/j.canlet.2005.07.003

Grbeša, Ivana, Mirko Ivkić, Boris Pegan and Koraljka Gall Trošelj. "Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma." Cancer Letters 238, no. 2 (2006): 224-229. https://doi.org/10.1016/j.canlet.2005.07.003

Grbeša, I., et al. (2006) 'Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma', Cancer Letters, 238(2), pp. 224-229. doi: 10.1016/j.canlet.2005.07.003

Grbeša I, Ivkić M, Pegan B, Gall Trošelj K. Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma. Cancer Letters [Internet]. 2006 July 18 [cited 2025 April 25];238(2):224-229. doi: 10.1016/j.canlet.2005.07.003

I. Grbeša, M. Ivkić, B. Pegan and K. Gall Trošelj, "Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma", Cancer Letters, vol. 238, no. 2, pp. 224-229, July 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:234174. [Accessed: 25 April 2025]

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Metadata
Title (english)Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma
AuthorIvana Grbeša
AuthorMirko Ivkić
AuthorBoris Pegan
AuthorKoraljka Gall-Trošelj
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The gene for insulin-like growth factor two, IGF2 is maternally imprinted. Fifteen heterozygous samples were analyzed for the IGF2 imprinting status and promoter usage. IGF2 LOI was detected in four non-tumorous tissues and in six laryngeal squamous cell carcinoma (LSCC) tumors. There was no clear pattern of specific promoter activity in LSCC tumors and the adjacent normal tissues. P1 promoter usage was active in eight LSCCs, among them four with LOI. As it was activated in four tumors with maintenance of imprinting (MOI) and four non-tumors, we concluded that P1 promoter is not exclusively connected with IGF2 LOI in LSCC.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleCancer Letters
Numberingvol. 238, no. 2, pp. 224-229
p-ISSN0304-3835
DOIhttps://doi.org/10.1016/j.canlet.2005.07.003
URN:NBNurn:nbn:hr:105:234174
Publication2006-07-18
Document URLhttps://doi.org/10.1016/j.canlet.2005.07.003
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 07:59:03