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Scientific paper - Original scientific paper
Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings
Collegium Antropologicum, 39 (2015), 3; 701-708. urn:nbn:hr:105:849845
Borović Šunjić, Suzana; Čipak Gašparović, Ana; Vuković, Tea; Weiss, Thomas; Sussman Weiss, Elisabeth; Soldo, Ivo; Đaković, Nikola; Žarković, Tomislav; Žarković, Neven

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Borović Šunjić, S., Čipak Gašparović, A., Vuković, T., Weiss, T., Sussman Weiss, E., Soldo, I. ... Žarković, N. (2015). Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings . Collegium Antropologicum, 39. (3), 701-708. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:849845

Borović Šunjić, Suzana, et al. "Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings ." Collegium Antropologicum, vol. 39, no. 3, 2015, pp. 701-708. https://urn.nsk.hr/urn:nbn:hr:105:849845

Borović Šunjić, Suzana, Ana Čipak Gašparović, Tea Vuković, Thomas Weiss, Elisabeth Sussman Weiss, Ivo Soldo, Nikola Đaković, Tomislav Žarković and Neven Žarković. "Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings ." Collegium Antropologicum 39, no. 3 (2015): 701-708. https://urn.nsk.hr/urn:nbn:hr:105:849845

Borović Šunjić, S., et al. (2015) 'Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings ', Collegium Antropologicum, 39(3), pp. 701-708. Available at: https://urn.nsk.hr/urn:nbn:hr:105:849845 (Accessed 02 February 2025)

Borović Šunjić S, Čipak Gašparović A, Vuković T, Weiss T, Sussman Weiss E, Soldo I, and sur.. Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings . Collegium Antropologicum [Internet]. 2015 September [cited 2025 February 02];39(3):701-708. Available at: https://urn.nsk.hr/urn:nbn:hr:105:849845

S. Borović Šunjić, et al., "Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings ", Collegium Antropologicum, vol. 39, no. 3, pp. 701-708, September 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:849845. [Accessed: 02 February 2025]

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Metadata
Title (english)Adjuvant cancer biotherapy by Viscum album extract Isorel: overview of evidence based medicine findings
Title (croatian)Adjuvantna onkološka bioterapija Viscum album ekstratom Isorel: prikaz nalaza temeljnih na medicinskim opažanjima
AuthorSuzana Borović Šunjić
AuthorAna Čipak Gašparović
AuthorTea Vuković
AuthorThomas Weiss
AuthorElisabeth Sussman Weiss
AuthorIvo Soldo
AuthorNikola Đaković
AuthorTomislav Žarković
AuthorNeven Žarković
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Within the integrative medicine one of the most frequently used adjuvant cancer biotherapies is based on aqueous mistletoe (Viscum album) extracts. Tumor growth inhibition, stimulation of host immune response and improvement of the quality of life are the positive effects of mistletoe therapy described in several preclinical and clinical studies. However, cumulative results of the evidence based medicine findings on such treatments are rarely given. Therefore, this paper evaluates the evidence based findings describing effects of the Viscum album extract Isorel in cancer therapy with respect to the type of therapy, stage and type of illness. This study presents cumulated data for 74 patients with different types and stages of cancer treated by Viscum album extract as adjuvant treatment to different conventional therapies, mostly combined surgery and radiotherapy. The biotherapy effectiveness was evaluated according to the outcome as (1) no major therapeutic improvement (15% of patients), (2) prevention of tumor recurrence (47% of patients) and (3) regression of cancer (38% of patients). Notably, there was no obvious health worsening during the follow up period at all. Thus, the results obtained for conventional anticancer therapies combined with adjuvant biotherapy based on Viscum album extract seem to be beneficial for the majority of cancer patients (85%) without serious side effects.
Abstract (croatian)
U okviru integrativne medicine jedan od najčešće korištenih oblika adjuvantne onkološke bioterapije se temelji na vodenim ekstraktima imele (Viscum album). U nizu pretkliničkih i kliničkih istraživanja opisani su pozitivni učinci terapije ekstraktima imele koji uključuju inhibiciju rasta tumora uz poticanje imunološkog sustava obrane oboljelih i poboljšanje kvalitete života. Međutim, sažimanje rezultata podataka dobivenih medicinskim opažanjima za različite oblike ovakvih tretmana u osoba oboljelih od različitih oblika tumora se rijetko opisuje. Stoga ovim radom analiziramo medicinska opažanja dobivena za bolesnike liječene ekstraktom Isorel ovisno o oblicima sveukupne onkološke terapije, stadiju bolesti i tipu zloćudnog tumora. Studija uključuje kumulativne podatke dobivene za 74 bolesnika s različitim oblicima malignoma, različitih stadija bolesti koji su uz Isorel primali različite oblike konvencionalne onkološke terapije, pretežito kombinaciju kirurškog zahvata i radioterapije. Uspješnost adjuvantne bioterapije je evaluirana prema ishodu kao 1) bez znatnijih terapijskih učinaka (15% bolesnika), 2) prevencija recidiva bolesti (47%), te nestanak bolesti (38%), pri čemu treba napomenuti da niti u jednog bolesnika nije zabilježeno pogoršanje zdravlja. Stoga dobiveni rezultati konvencionalnih onkoloških terapija u kombinaciji s adjuvantnom terapijom Isorelom ukazuju na korisnost ovakvog integrativnog medicinskog pristupa u 85% onkoloških bolesnika, bez neželjenih popratnih pojava.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 39, no. 3, pp. 701-708
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:849845
Publication2015-09
Document URLhttps://hrcak.srce.hr/166282
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:31:07