prikaz prve stranice dokumenta Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation
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Scientific paper - Original scientific paper
Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation
Kidney & Blood Pressure Research, 41 (2016), 6; 781-793. https://doi.org/10.1159/000450568
Bašić-Jukić, Nikolina; Gulin, Marijana; Hudolin, Tvrtko; Kaštelan, Željko; Katalinić, Lea; Ćorić, Marijana; Varnai, Veda Marija; Ivković, Vanja; Kes, Petar; Jelaković, Bojan

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Bašić Jukić, N., Gulin, M., Hudolin, T., Kaštelan, Ž., Katalinić, L., Ćorić, M. ... Jelaković, B. (2016). Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation. Kidney & Blood Pressure Research, 41. (6), 781-793. doi: 10.1159/000450568

Bašić Jukić, Nikolina, et al. "Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation." Kidney & Blood Pressure Research, vol. 41, no. 6, 2016, pp. 781-793. https://doi.org/10.1159/000450568

Bašić Jukić, Nikolina, Marijana Gulin, Tvrtko Hudolin, Željko Kaštelan, Lea Katalinić, Marijana Ćorić, Veda Marija Varnai, Vanja Ivković, Petar Kes and Bojan Jelaković. "Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation." Kidney & Blood Pressure Research 41, no. 6 (2016): 781-793. https://doi.org/10.1159/000450568

Bašić Jukić, N., et al. (2016) 'Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation', Kidney & Blood Pressure Research, 41(6), pp. 781-793. doi: 10.1159/000450568

Bašić Jukić N, Gulin M, Hudolin T, Kaštelan Ž, Katalinić L, Ćorić M, and sur.. Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation. Kidney & Blood Pressure Research [Internet]. 2016 [cited 2024 December 20];41(6):781-793. doi: 10.1159/000450568

N. Bašić Jukić, et al., "Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation", Kidney & Blood Pressure Research, vol. 41, no. 6, pp. 781-793, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:296598. [Accessed: 20 December 2024]

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Metadata
Title (english)Expression of BMP-2 in vascular endothelial cells of recipient may predict delayed graft function after renal transplantation
AuthorNikolina Bašić-Jukić
AuthorMarijana Gulin
AuthorTvrtko Hudolin
AuthorŽeljko Kaštelan
AuthorLea Katalinić
AuthorMarijana Ćorić
AuthorVeda Marija Varnai
AuthorVanja Ivković
AuthorPetar Kes
AuthorBojan Jelaković
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND/AIMS: Delayed graft function (DGF) is associated with adverse outcomes after renal transplantation. Bone morphogenetic protein-2 (BMP-2) is involved in both endothelial function and immunological events. We compared expression of BMP-2 in epigastric artery of renal transplant recipients with immediate graft function (IGF) and DGF. ----- METHODS: 79 patients were included in this prospective study. Patients were divided in IGF group (64 patients) and DGF group (15 patients). BMP-2 expression in intima media (BMP2m) and endothelium (BMP2e) of epigastric artery was assessed by immunohistochemistry. ----- RESULTS: Lower intensity of BMP2e staining was recorded in DGF compared to IGF. In DGF patients, 93% had no expression of BMP2e and 7% had 1st grade expression, compared to 45% and 41% in IGF group, respectively (P=0.001) (P<0.001 for no expression and P = 0.015 for 1st grade expression). Patients who had BMP2e staining positive had lower odds for DGF (OR 0.059 [0.007, 0.477]) and this remained significant even after adjustment for donor and recipient variables, cold ischemia time, and immunological matching (OR 0.038 [0.003, 0.492]). ----- CONCLUSIONS: Our results demonstrate that BMP-2 expression in endothelial cells of epigastric arteries may predict development of DGF.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleKidney & Blood Pressure Research
Numberingvol. 41, no. 6, pp. 781-793
p-ISSN1420-4096
DOIhttps://doi.org/10.1159/000450568
URN:NBNurn:nbn:hr:105:296598
Publication2016
Document URLhttps://doi.org/10.1159/000450568
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 09:14:17