prikaz prve stranice dokumenta Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients
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Scientific paper - Original scientific paper
Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients
The International Journal of Cardiovascular Imaging, 34 (2018), 10; 1647-1655. https://doi.org/10.1007/s10554-018-1376-3
Medaković, Petar; Biloglav, Zrinka; Padjen, Ivan; Pristaš, Ivan; Jukić, Mladen; Žuvela, Franko; Ivanac, Gordana; Brkljačić, Boris; Jukić, Tena; Turk, Lana

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Medaković, P., Biloglav, Z., Padjen, I., Pristaš, I., Jukić, M., Žuvela, F. ... Turk, L. (2018). Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients. The International Journal of Cardiovascular Imaging, 34. (10), 1647-1655. doi: 10.1007/s10554-018-1376-3

Medaković, Petar, et al. "Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients." The International Journal of Cardiovascular Imaging, vol. 34, no. 10, 2018, pp. 1647-1655. https://doi.org/10.1007/s10554-018-1376-3

Medaković, Petar, Zrinka Biloglav, Ivan Padjen, Ivan Pristaš, Mladen Jukić, Franko Žuvela, Gordana Ivanac, Boris Brkljačić, Tena Jukić and Lana Turk. "Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients." The International Journal of Cardiovascular Imaging 34, no. 10 (2018): 1647-1655. https://doi.org/10.1007/s10554-018-1376-3

Medaković, P., et al. (2018) 'Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients', The International Journal of Cardiovascular Imaging, 34(10), pp. 1647-1655. doi: 10.1007/s10554-018-1376-3

Medaković P, Biloglav Z, Padjen I, Pristaš I, Jukić M, Žuvela F, and sur.. Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients. The International Journal of Cardiovascular Imaging [Internet]. 2018 October [cited 2024 November 13];34(10):1647-1655. doi: 10.1007/s10554-018-1376-3

P. Medaković, et al., "Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients", The International Journal of Cardiovascular Imaging, vol. 34, no. 10, pp. 1647-1655, October 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:358436. [Accessed: 13 November 2024]

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Metadata
Title (english)Quantification of coronary atherosclerotic burden with coronary computed tomography angiography: adapted Leaman score in Croatian patients
AuthorPetar Medaković
AuthorZrinka Biloglav
AuthorIvan Padjen
AuthorIvan Pristaš
AuthorMladen Jukić
AuthorFranko Žuvela
AuthorGordana Ivanac
AuthorBoris Brkljačić
AuthorTena Jukić
AuthorLana Turk
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of the study was to quantify the total coronary atherosclerotic burden in patients with suspected coronary artery disease (CAD) defined by coronary computed tomography adapted Leaman score (CT-LeSc) and to estimate its cut-off level for high coronary atherosclerotic burden. We enrolled 434 consecutive patients referred to coronary computed tomography angiography, of which 261 patients fulfilled the study inclusion criteria. Demographic and clinical characteristics, as well as CAD risk factors were obtained. CAD pre-test probabilities were estimated by the Diamond-Forrester model and Morise score. The coronary atherosclerotic burden was estimated using CT-LeSc. As a cut-off for a high coronary atherosclerotic burden, we used 3rd tercile (Tc3) (CT-LeSc ≥ 5.52). We evaluated the association of clinical characteristics and risk factors with Tc3 in univariate and multivariate analysis. There were 60.9% males and 39.1% females, 81% of patients had above-normal weight, 68.2% hypertension, 54.0% dyslipidemia, 15.3% diabetes mellitus, 12.3% positive smoking history and 11.9% had a family history of CAD. According to the Diamond-Forrester model and Morise score the majority of patients had intermediate risk, 59.7 and 52.8%, followed by the high-risk group, 36.0 and 34.4%, respectively. Age, dyslipidemia, hypertension and pre-test risk scores in the univariate analysis significantly predicted Tc3. In the multivariate analysis, male sex (p = 0.004), dyslipidemia (p = 0.002) and coronary calcium score (< 0.001) were identified as predictors of Tc3. CT-LeSc quantified the total coronary atherosclerotic burden and showed an association of risk factors and pre-test probabilities with Tc3.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleThe International Journal of Cardiovascular Imaging
Numberingvol. 34, no. 10, pp. 1647-1655
p-ISSN1569-5794
DOIhttps://doi.org/10.1007/s10554-018-1376-3
URN:NBNurn:nbn:hr:105:358436
Publication2018-10
Document URLhttp://doi.org/10.1007/s10554-018-1376-3
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:26:33