Position statement for the diagnosis and management of anogenital warts

Professional paper - Professional paper

• Author: C. O'Mahony
• Author: M. Gomberg
• Author: Mihael Skerlev
• Author: A. Alraddadi
• Author: M.E. Heras‐Alonso
• Author: S. Majewski
• Author: E. Nicolaidou
• Author: S. Serdaroğlu
• Author: Z. Kutlubay
• Author: M. Tawara
• Author: A. Stary
• Author: A. Al Hammadi
• Author: M. Cusini
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Background: Anogenital warts (AGW) can cause economic burden on healthcare systems and are associated with emotional, psychological and physical issues.
----- Objective: To provide guidance to physicians on the diagnosis and management of AGW.
----- Methods: Fourteen global experts on AGW developed guidance on the diagnosis and management of AGW in an effort to unify international recommendations. Guidance was developed based on published international and national AGW guidelines and an evaluation of relevant literature published up to August 2016. Authors provided expert opinion based on their clinical experiences.
----- Results: A checklist for a patient's initial consultation is provided to help physicians when diagnosing AGW to get the relevant information from the patient in order to manage and treat the AGW effectively. A number of frequently asked questions are also provided to aid physicians when communicating with patients about AGW. Treatment of AGW should be individualized and selected based on the number, size, morphology, location, and keratinization of warts, and whether they are new or recurrent. Different techniques can be used to treat AGW including ablation, immunotherapy and other topical therapies. Combinations of these techniques are thought to be more effective at reducing AGW recurrence than monotherapy. A simplified algorithm was created suggesting patients with 1-5 warts should be treated with ablation followed by immunotherapy. Patients with >5 warts should use immunotherapy for 2 months followed by ablation and a second 2-month course of immunotherapy. Guidance for daily practice situations and the subsequent action that can be taken, as well as an algorithm for treatment of large warts, were also created.
----- Conclusion: The guidance provided will help physicians with the diagnosis and management of AGW in order to improve the health and quality of life of patients with AGW.

• Keywords (english): Anus Diseases / diagnosis; Anus Diseases / therapy; Condylomata Acuminata / diagnosis; Condylomata Acuminata / therapy; Female; Genital Diseases, Female / diagnosis; Genital Diseases, Female / therapy; Genital Diseases, Male / diagnosis; Genital Diseases, Male / therapy; Humans; Male; Papillomavirus Infections / diagnosis; Papillomavirus Infections / therapy; Practice Guidelines as Topic
• Language: english
• Publication type: Professional paper - Professional paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Journal of the European Academy of Dermatology and Venereology
• Numbering: vol. 33, no. 6, pp. 1006-1019
• p-ISSN: 0926-9959
• DOI: https://doi.org/10.1111/jdv.15570
• URN:NBN: urn:nbn:hr:105:690438
• Publication: 2019-06
• Document URL: http://doi.org/10.1111/jdv.15570
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 10:36:14