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Scientific paper - Original scientific paper
Esomeprazole versus pantoprazole for healing erosive oesophagitis
Collegium Antropologicum, 30 (2006), 3; 519-522. urn:nbn:hr:105:252004
Včev, Aleksandar; Begić, Ivana; Ostojić, Rajko; Jurčić, Dragan; Božić, Dubravko; Soldo, Ivan; Gmajnić, Rudika; Kondža, Goran; Khaznadar, Eyad; Mićunović, Nikola

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Včev, A., Begić, I., Ostojić, R., Jurčić, D., Božić, D., Soldo, I. ... Mićunović, N. (2006). Esomeprazole versus pantoprazole for healing erosive oesophagitis. Collegium Antropologicum, 30. (3), 519-522. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:252004

Včev, Aleksandar, et al. "Esomeprazole versus pantoprazole for healing erosive oesophagitis." Collegium Antropologicum, vol. 30, no. 3, 2006, pp. 519-522. https://urn.nsk.hr/urn:nbn:hr:105:252004

Včev, Aleksandar, Ivana Begić, Rajko Ostojić, Dragan Jurčić, Dubravko Božić, Ivan Soldo, Rudika Gmajnić, Goran Kondža, Eyad Khaznadar and Nikola Mićunović. "Esomeprazole versus pantoprazole for healing erosive oesophagitis." Collegium Antropologicum 30, no. 3 (2006): 519-522. https://urn.nsk.hr/urn:nbn:hr:105:252004

Včev, A., et al. (2006) 'Esomeprazole versus pantoprazole for healing erosive oesophagitis', Collegium Antropologicum, 30(3), pp. 519-522. Available at: https://urn.nsk.hr/urn:nbn:hr:105:252004 (Accessed 14 April 2025)

Včev A, Begić I, Ostojić R, Jurčić D, Božić D, Soldo I, and sur.. Esomeprazole versus pantoprazole for healing erosive oesophagitis. Collegium Antropologicum [Internet]. 2006 September [cited 2025 April 14];30(3):519-522. Available at: https://urn.nsk.hr/urn:nbn:hr:105:252004

A. Včev, et al., "Esomeprazole versus pantoprazole for healing erosive oesophagitis", Collegium Antropologicum, vol. 30, no. 3, pp. 519-522, September 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:252004. [Accessed: 14 April 2025]

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Metadata
Title (english)Esomeprazole versus pantoprazole for healing erosive oesophagitis
AuthorAleksandar Včev
AuthorIvana Begić
AuthorRajko Ostojić
AuthorDragan Jurčić
AuthorDubravko Božić
AuthorIvan Soldo
AuthorRudika Gmajnić
AuthorGoran Kondža
AuthorEyad Khaznadar
AuthorNikola Mićunović
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of this study was to compare the efficacy of esomeprazole and pantoprazole with regard to healing and relief from gastroesophageal reflux disease-related symptoms. I this multicentre, randomized, single-blind study 180 patients (ITT population) diagnosed with endoscopically proven GERD grade A,B,C received esomeprazole (40 mg once daily (o.d.), n = 90) orpantoprazole (40 mg o.d., n = 90). Healing and relief from GERD-related symptoms were assessed at first and final visit (after 4 or 8 weeks of treatment). Esomeprazole 40 mg provided significantly greater healing than pantoprazole 40 mg after 4 weeks of treatment in patients with EE (77.8% vs. 72.2%). Esomeprazole-treated patients were healed after up to 8 weeks of treatment similar those treated with pantoprazole (92.2% vs. 91.1%). The proportion of heartburn-free days was similar in patients treated with esomeprazole and to those treated with pantoprazole.
Abstract (croatian)
Cilj ovog rada je bio komparirati učinkovitost esomeprazola i pantoprazola u cijeljenju erozivnog ezofagitisa (EE) i nestanku simptoma gastroezofagealne refluksne bolesti (GERB). U ovu multicentričnu, randomiziranu, jednostruko slijepu studiju je bilo uključeno 180 bolesnika s endoskopski dijagnosticiranim GERB-om i dobivali su esomeprazol 40 mg/dan (90 bolesnika) ili pantoprazol 40 mg/dan (90 bolesnika). Nakon 4. i 8. tjedna terapije kontrolirani su radi dokaza cijeljenja EE i nestanka simptoma GERB-a. Esomeprazol bio je statistički značajno učinkovitiji od pantoprazola u cijeljenju EE nakon 4 tjedna liječenja (77.8% nasuprot 72.2%). Nakon 8 tjedana liječenja učinkovitost im je bila podjednaka (92.2% nasuprot 91.1%). Postotak bolesnika bez simptoma GERB-a je bio podjednak nakon 4. i 8. tjedna liječenja u obje skupine.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 30, no. 3, pp. 519-522
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:252004
Publication2006-09
Document URLhttps://hrcak.srce.hr/27602
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:58:43