Lower gastrointestinal disorders in patients with irritable bowel syndrome

Scientific paper - Original scientific paper

• Author: Dragan Jurčić
• Author: Ante Bilić
• Author: Dragan Schwarz
• Author: Krešimir Luetić
• Author: Marinko Marušić
• Author: Aleksandar Včev
• Author: Maruška Gabrić
• Author: Ljubica Špoljarić
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal system characterized by abdominal pain related to bowel emptying, defecation impairment and abdominal distention. The aim of the study was to objectify lower gastrointestinal system disturbances in IBS patients. Thirty IBS patients and 30 healthy subjects were included in the study. IBS patients were divided into two subgroups: IBS with predominant diarrhea (IBSd) and IBS with predominant constipation (IBSc). All study subjects underwent physical examination (including digitorectal examination), standard laboratory testing and anorectal manometry. Endoscopy was performed only in group of IBS patients. A statistically significant difference was recorded in most manometric parameters between healthy subjects and IBS patients, which was even more pronounced in IBSd patients. Study results showed that the intestinal motility disorder underlying IBS could be objectified by use of anorectal manometry.

Abstract (croatian)

Sindrom iritabilnog crijeva (SIC) funkcijski je poremećaj probavnog sustava koji karakterizira bol u abdomenu povezana sa defekacijom, poremećaji defekacije te distenzija trbuha. Našim istraživanjem željeli smo objektivizirati promjene u donjim dijelovima gastrointestinalnog trakta u bolesnika sa sindromom iritabilnog crijeva. U istraživanje je uključeno trideset bolesnika sa SIC i 30 zdravih ispitanika. Bolesnici sa SIC podijeljeni su u dvije podskupine: prva (SICp) s predominantnim proljevom i druga (SICk) s dominantnom konstipacijom. Svim ispitanicima učinjen je fizikalni pregled (uključujući digitorektalni), standardno laboratorijsko testiranje, anorektalna manometrija, a bolesnicima sa SIC i endoskopija. Rezultati su pokazali da postoji statistički značajna razlika u većini manometrijskih parametara u bolesnika sa SIC, dok je razlika još izraženija u bolesnika sa SICp. Naše istraživanje pokazuje da upotrebljavajući anorektalnu manometriju možemo objektivizirati poremećaj motiliteta crijeva koji i jest u podlozi SIC-a.

• Keywords (english): Lower Gastrointestinal Tract; Gastrointestinal Diseases - diagnosis - etiology - physiopathology; Irritable Bowel Syndrome - complications - diagnosis; Adult; Female; Gastrointestinal Motility; Humans; Male; Manometry
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 32, no. 3, pp. 755-759
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:756731
• Publication: 2008-09
• Document URL: https://hrcak.srce.hr/27060
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 11:06:21