Spontaneous tendon ruptures in patients with end-stage renal disease

Scientific paper - Original scientific paper

• Author: Nikolina Bašić-Jukić
• Author: Ivana Jurić
• Author: Sanjin Rački
• Author: Petar Kes
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Spontaneous tendon ruptures in patients with end-stage renal disease (ESRD) have been reported rarely. We describe the largest own group of patients with spontaneous rupture of major tendons. Rupture of 16 tendons occurred in 9 patients. Mean patient age was 52.78 years; 77.7 % were male. Four patients were treated with hemodialysis, four received renal transplant and one was treated with automated peritoneal dialysis. Bilateral rupture was found in 5 patients (3 quadriceps, one Achilles and one supraspinatus and subscapularis tendon rupture). Distal brachial biceps tendon rupture, Achilles tendon rupture, unilateral quadriceps, and rupture of the oblique internal abdominal muscle tendon were developed by one patient each. Patients were treated with renal replacement therapy for 3 to 21 years (mean 12.89). Five patients were treated with steroids and 6 patients received quinolone antibiotic before the tendon rupture. All patients had laboratory and clinical signs of hyperparathyroidism. A patient who was treated with APD for 3 years had primary hyperparathyroidism with nephrolithiasis as the cause of ESRD. Our results demonstrated that patients with hyperparathyroidism are at increased risk for development of spontaneous tendon ruptures, and the risk is further amplified when they receive quinolone antibiotics and/or steroids.

• Keywords (english): Female; Humans; Hyperparathyroidism/complications; Kidney Failure, Chronic/complications; Kidney Failure, Chronic/therapy; Male; Middle Aged; Quinolones/adverse effects; Renal Replacement Therapy; Rupture, Spontaneous/etiology; Steroids/adverse effects; Tendon Injuries/pathology
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Accepted version
• Journal title: Kidney & Blood Pressure Research
• Numbering: vol. 32, no. 1, pp. 32-36
• p-ISSN: 1420-4096
• DOI: https://doi.org/10.1159/000201792
• URN:NBN: urn:nbn:hr:105:957303
• Publication: 2009-02-12
• Document URL: https://doi.org/10.1159/000201792
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 11:12:55