Fetal macrosomia in pregnant women with gestational diabetes

Scientific paper - Original scientific paper

• Title (croatian): Fetalna makrosomija u trudnica s gestacijskim dijabetesom
• Author: Jadranko Šegregur
• Author: Damir Buković
• Author: Darko Milinović
• Author: Slavko Orešković
• Author: Jasminka Pavelić
• Author: Tomislav Župić
• Author: Jasminka Peršec
• Author: Mato Pavić
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

The aim of the study was to determine the frequency of fetal macrosomia in newborns from mothers with gestational diabetes mellitus (GDM) and healthy mothers, as well as determining the influence of fetal growth on pregnancy termination, on complications in pregnancy, during delivery and puerperium and on neonatal complications. In the study were included 351 pregnant women with GDM, as well as control group of 1502 healthy pregnant women. Newborns of mothers with GDM had significantly higher birth weight and length, ponderal index >2.85 was more frequent, they were macrosomic and hypertrophic (disproportional and proportional), had smaller Apgar score and more frequent neonatal complications (p<0.05). Fetal macrosomia and fetal hypertrophy alone or, particularly, connected with disproportional fetal growth, but disproportional hypotrophy as well, had significantly influence on greater frequency of delivery and puerperal complications, delivery completion with Cesarean section and neonatal complications in pregnant women with GDM.

Abstract (croatian)

Cilj rada je bio utvrditi učestalost fetalne makrosomije u novorođenčadi rođenih od majki koje boluju od gestacijskog dijabetesa melitusa (GDM) i zdravih majki, kao i utjecaj fetalnog rasta na način dovršenja trudnoće i učestalost komplikacija u trudnoći, porodu i puerperiju, te neonatalnih komplikacija. U istraživanje je uključeno 351 trudnica s GDM i 1502 zdrave trudnice kao kontrolna skupina. Novorođenčad trudnica s GDM su značajno veće porodne težine i duljine, učestalijeg PI>2,85, makrosomna su i hipertrofična (disproporcionalno i proporcionalno), imaju manje vrijednosti Apgar indeksa i veću učestalost neonatalnih komplikacija. (p<0,05). Fetalna makrosomija i fetalna hipertrofija same, posebice udružene s disproporcionalnim fetalnim rastom, ali i disproporcionalna hipotrofija, imaju značajan utjecaj na povećanu učestalost komplikacija u porodu i puerperiju, dovršenja poroda SC i neonatalnih komplikacija u trudnica s GDM.

• Keywords (english): Adult; Case-Control Studies; Croatia/epidemiology; Diabetes, Gestational/epidemiology; Female; Fetal Development; Fetal Macrosomia/epidemiology; Humans; Infant, Newborn; Male; Pregnancy; Pregnancy Outcome; Prospective Studies
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 33, no. 4, pp. 1121-1127
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:350135
• Publication: 2009-12
• Document URL: https://hrcak.srce.hr/51471
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 11:37:34