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Scientific paper - Original scientific paper
Myasthenia gravis patients with anti-MuSK antibodies
Collegium Antropologicum, 33 (2009), 4; 1151-1154. urn:nbn:hr:105:345446
Žagar, Marija; Vranješ, Davorka; Šoštarko, Marija; Vogrinc, Željka; Bilić, Ervina; Trbojević Čepe, Milica

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Žagar, M., Vranješ, D., Šoštarko, M., Vogrinc, Ž., Bilić, E. & Trbojević Čepe, M. (2009). Myasthenia gravis patients with anti-MuSK antibodies . Collegium Antropologicum, 33. (4), 1151-1154. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:345446

Žagar, Marija, et al. "Myasthenia gravis patients with anti-MuSK antibodies ." Collegium Antropologicum, vol. 33, no. 4, 2009, pp. 1151-1154. https://urn.nsk.hr/urn:nbn:hr:105:345446

Žagar, Marija, Davorka Vranješ, Marija Šoštarko, Željka Vogrinc, Ervina Bilić and Milica Trbojević Čepe. "Myasthenia gravis patients with anti-MuSK antibodies ." Collegium Antropologicum 33, no. 4 (2009): 1151-1154. https://urn.nsk.hr/urn:nbn:hr:105:345446

Žagar, M., et al. (2009) 'Myasthenia gravis patients with anti-MuSK antibodies ', Collegium Antropologicum, 33(4), pp. 1151-1154. Available at: https://urn.nsk.hr/urn:nbn:hr:105:345446 (Accessed 05 May 2024)

Žagar M, Vranješ D, Šoštarko M, Vogrinc Ž, Bilić E, Trbojević Čepe M. Myasthenia gravis patients with anti-MuSK antibodies . Collegium Antropologicum [Internet]. 2009 December [cited 2024 May 05];33(4):1151-1154. Available at: https://urn.nsk.hr/urn:nbn:hr:105:345446

M. Žagar, D. Vranješ, M. Šoštarko, Ž. Vogrinc, E. Bilić and M. Trbojević Čepe, "Myasthenia gravis patients with anti-MuSK antibodies ", Collegium Antropologicum, vol. 33, no. 4, pp. 1151-1154, December 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:345446. [Accessed: 05 May 2024]

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Metadata
Title (english)Myasthenia gravis patients with anti-MuSK antibodies
Title (croatian)Miastenija gravis kod bolesnika s pozitivnim protutijelima na MuSK
AuthorMarija Žagar
AuthorDavorka Vranješ
AuthorMarija Šoštarko
AuthorŽeljka Vogrinc
AuthorErvina Bilić
AuthorMilica Trbojević Čepe
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
In myasthenia gravis (MG) patients without detectable anti-acetylcholine receptor (anti-AChR) antibody, referred to as seronegative myasthenia gravis patients, there is a variable proportion of patients with antibodies against the muscle specific kinase (MuSK). MuSK antibodies were found in 8 (29.6%) of our 27 patients with generalized MG without anti-AChR antibodies. All these patients were female. The age at the onset ranged from 22 to 38 years. All patients had ocular and bulbar symptoms, and two patients also had generalized limb weakness. Two patients had pure ocular symptoms for 7 or 8 years before the development of bulbar symptoms. All anti-MuSK positive patients were treated with immunosuppressive drugs, three received plasmapheresis and one patient required mechanical ventilation. Our results are consistent with other literature reports.
Abstract (croatian)
Bolesnici s miastenijom gravis (MG) kod kojih se ne na|u protutijela na acetilkolinske receptore (AChR) referiraju se kao bolesnici sa seronegativnom miastenijom gravis. Ti bolesnici u različitom postotku imaju pozitivna protutijela na specifičnu mišićnu kinazu (MuSK). Protutijela na MuSK bila su pozitivna kod 8 od 27 naših bolesnika s MG (29,6%) kod kojih nisu na|ena protutijela na AChR. Svi naši bolesnici su bile žene. Simptomi MG su se javili u dobi od 22–38 godina. Sve bolesnice su imale očne i bulbarne simptome, a dvije su imale i generaliziranu slabost u rukama i nogama. Dvije su bolesnice imale samo okularne simptome 7 odnosno 8 godina prije pojave bulbarnih simptoma. Sve su liječene imunosupresivnom terapijom, tri su bolesnice liječene plazmaferezom, a jedna je u jednom razdoblju trebala i mehaničku ventilaciju. Naši rezultati su slični rezultatima ostalih autora.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 33, no. 4, pp. 1151-1154
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:345446
Publication2009-12
Document URLhttps://hrcak.srce.hr/51480
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:37:44